Roles of Two Sphingomyelin Synthase Isoforms in Murine Hair

    September 2016 in “ Journal of Dermatological Science ”
    Takeshi Ichikawa, Akihito Nishi, Shota Sakai, Asami Makino, Yoshihiro Tokudome, Tadashi Yamashita, Toshiro Okazaki, Yoshikazu Uchida, Takaaki Tsuchida, Yoshio Hirabayashi, Sumiko Hamanaka
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    TLDR Both SMS1 and SMS2 are crucial for normal hair growth and cycle in mice.
    The study "Roles of two sphingomyelin synthase isoforms in murine hair" conducted by Takeshi Ichikawa, Shota Sakai, and Sumiko Hamanaka, investigated the role of two sphingomyelin synthase isoforms, SMS1 and SMS2, in murine hair. The researchers found that SMS1 and SMS2 have distinct roles in the hair cycle. SMS1 was found to be necessary for the initiation of the anagen phase (growth phase) of the hair cycle, while SMS2 was necessary for the maintenance of the anagen phase. The study concluded that both SMS1 and SMS2 are crucial for normal hair growth and cycle in mice. The number of mice used in the study was not specified.
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