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Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Injected human hair follicle cells can create new, small hair follicles in skin cultures.

Thyroid function affects skin health, with a complex interaction between the two.

Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.

S100A3 protein is crucial for hair shaft formation in mice.

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.

Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

The skin and thymus develop similarly to protect and support immunity.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.

Pro-IGF-II improves muscle repair in old mice.

Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.