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This study explored the solubility and crystal structure of GI197111X, a 5-alpha reductase inhibitor for androgenetic alopecia, finding its solubility in Capmul MCM suitable for a soft gel dosage form.

This study developed a herbal-based anti-dandruff shampoo using a combination of eleven plant extracts and found that it demonstrated safe, stable, and effective anti-dandruff and cleansing properties, without the adverse effects associated with synthetic shampoos.

This study found that the Qing Cuo Formula significantly reduced serum androgen and inflammatory cytokine levels in hamsters with damp-heat acne and identified potential molecular mechanisms and active compounds involved.

In this study, researchers found that finasteride exhibits a solid-solid phase relationship that is enantiotropic at normal pressure and becomes monotropic at higher pressure.

This review describes advanced drug delivery systems for dithranol aimed at overcoming stability issues and skin irritation seen in conventional formulations, highlighting options like nanoparticles and liposomes for improved psoriasis treatment.

This study developed and validated a second derivative spectrophotometric method for accurately estimating tamsulosin and finasteride in bulk and pharmaceutical formulations.

This discussion reviews a hybrid phase I-II/III clinical trial design that enables dose re-optimization in phase III, but reports no new findings.

This in-silico study identified several compounds as potential Vitamin D Receptor agonists, with Dolichosterone showing the strongest binding energy.

In this study, complexation with cyclodextrins was reported to increase the solubility of FIN for potential use in aqueous formulations for treating male androgenic alopecia.

This study reported that the formulated herbal anti-dandruff shampoo demonstrated satisfactory cleansing and conditioning properties, comparable to standard synthetic shampoos, but further testing is needed to confirm its long-term safety.

This invention reports piperazine derivatives as potent inhibitors of type 3 17β-hydroxysteroid dehydrogenase, suggesting potential therapeutic applications in treating prostate cancer, acne, and androgenic alopecia.

In this study, researchers developed an emulgel formulation containing minoxidil for hair growth, using chitosan and fucoidan as gelling agents, achieving controlled drug release with 99.7% released by the 12th hour.

This report suggests that for prostate cancer patients with cardiovascular disease, prescribing the GnRH antagonist degarelix may reduce cardiac events compared to using GnRH agonists, although prescribing should consider potential cardiac risks, particularly in patients with pre-existing conditions or older age.

This study found that 3alpha-diol, an androgen metabolite, improved cognitive and affective performance in aged male rats, suggesting its role in countering age-related decline in hippocampally-influenced behaviors.

This study describes a new radiation method called three-dimensional moving field radiation therapy, which showed improved tumor targeting and reduced damage to surrounding tissues compared to traditional one-plane methods.

This study successfully synthesized acetyl tetrapeptide-3 on a laboratory scale with over 56% yield and 100% purity, supporting its use in developing hair loss and scalp care products.

This study found that a hair serum formulated with extracts of Murraya koenigii and Clitoria ternatea demonstrated strong antifungal activity and effective dandruff management, based on laboratory evaluations.

This study found that the Arabidopsis thaliana protein Formin 2 localizes to plasmodesmata and is crucial for regulating their permeability by anchoring actin filaments, which affects virus susceptibility.

This study developed a new analytical method to identify a wide range of endocrine disrupting compounds in full-term amniotic fluid, revealing diverse substances with potential endocrine activity.

In this study, experts propose a diagnostic and treatment guideline for folliculitis decalvans, emphasizing the role of trichoscopy and introducing a therapeutic algorithm tailored to disease activity, which is significant for clinical management given the lack of specific clinical trials.

In this study, a hair tonic containing fragrant pandan leaf extract and virgin coconut oil was formulated and evaluated, with most variations demonstrating physical stability except for one formulation, which showed instability in the specific gravity test.

This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.

This study tested a folate-conjugate drug delivery system and found its cytotoxicity depends on whether the treated cells overexpress folate receptors, suggesting potential for targeted chemotherapy.

This article describes a new synthesis method for finasteride that reduces the use of costly and toxic reagents, making it more suitable for large-scale production, but reports no clinical results.

This study found that protein hydrolysates from mealworms, especially those derived using flavourzyme, significantly enhance adipogenic differentiation in 3T3-L1 preadipocytes, suggesting their potential as sustainable ingredients for glycemic control, skin health, and tissue regeneration products.

This study introduces an efficient ghost-cell based immersed boundary method for simulating fluid-particle mass transfer, capable of accurately handling mixed boundary conditions at particle surfaces.

In this study, researchers developed an orange peel-based organic hair serum and found that among tested formulations, F3 showed better stability, phytochemical content, and overall effectiveness, suggesting potential for enhancing hair texture, reducing dandruff, and promoting healthy growth while being environmentally friendly.

In this study, two different estroprogestin treatments significantly improved skin conditions and decreased androgen levels in hyperandrogenic women, with EE/DRSP showing more pronounced hormonal changes and skin improvements compared to EE/CMA.

In this study, researchers conducted additional IHC staining on equine skin sections and found that collagen type III primarily labels the extracellular matrix, while anti-PDGFR-antibody staining highlights cells with long-shaped processes mainly arranged around hair follicles.

This case report describes a 54-year-old woman with familial dyskeratotic comedones who experienced slight improvement in her skin lesions after three months of treatment with topical retinoids and urea cream.