Total Synthesis of the Active Ingredient Acetyl Tetrapeptide-3 for Hair Loss Treatment and Scalp Care

    March 2025 in “ Journal of Science Natural Science ”
    Hai-Binh Bui, David Hung-Tsang Yen, Huy Luong Xuan, Le Thi Phuong Hoa
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    TLDR Acetyl tetrapeptide-3 was successfully made for use in hair loss treatments.
    The study successfully synthesized acetyl tetrapeptide-3, a key ingredient for hair loss treatment and scalp care, using solid-phase peptide synthesis. The synthesis achieved a yield of over 56% and a purity of 100%, as confirmed by high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS). This research supports the development of cosmetic products incorporating acetyl tetrapeptide-3 as an active agent for combating hair loss.
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