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Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

Trichoscopy is a useful non-invasive method for diagnosing different hair loss conditions.

Keratins are crucial for cell structure, growth, and disease risk.

Fingerprints form uniquely before birth due to specific genetic pathways and local signals.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Human hair follicle dermal cells can effectively replace other cells in engineered skin.

Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.

The document reports a unique case of woolly hair with a combination of conditions not previously seen together.

Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.

Changthangi goats have specific genes that help produce Pashmina wool.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

The guide helps doctors diagnose hair problems by suggesting a thorough patient history, physical exams, and various diagnostic tools.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Hair's strength and flexibility come from its protein structure and molecular interactions.

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

Key genes linked to hair growth and cancer were identified in hairless mice.

A new 3D culture system helps grow and study mouse skin stem cells for a long time.