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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Hair follicles help substances penetrate the skin faster and more effectively.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

Effective treatments for common hair loss are limited and may have side effects, leading to patient disappointment and treatment discontinuation.

Minoxidil foam enters hair follicles and skin for hair growth.

Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Finasteride cream helps hair growth with less side effects.

Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.

Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.

Excipients greatly affect how well curcumin nanocrystals penetrate the skin and target hair follicles.

Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.

Some skin medications are safe for pregnant women, but others pose risks or should not be used.

Fullerenes show potential in skin care but need more safety research.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

The steroid solution can regrow hair but often causes skin issues and doesn't work long-term.

Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.

Cancer survivors often experience worse skin problems from treatment than expected, and working with dermatologists could help improve their condition.

Various local treatments for alopecia areata show promise, but individualized plans and more research are needed.

Hair follicles help magnesium get through the skin more effectively.

Lichen sclerosus et atrophicus is generally not considered precancerous, but there are exceptions.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Dermabrasion improves skin appearance by removing the top layer to promote healing.

Men are increasingly using energy-based skin treatments for workplace success, with lasers and other devices effectively improving skin and body appearance.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.