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The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

Hair loss may indicate higher heart risk and metabolic issues.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Chicken feather gene mutation helps understand human hair disorders.

Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

Hair loss can be a key sign of a rare type of rickets when vitamin D treatment doesn't work and advanced tests aren't available.

The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Fzd2 is important for skin and hair development through various signaling ways.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.

Silk proteins are great for cosmetics because they protect and improve skin and hair while being eco-friendly.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

Polyomavirus A2 infection in newborn mice caused hair follicle tumors.

Aging affects hair density and skin health, and Behcet's disease, a complex condition with no specific test, involves sores and systemic issues, treated with various medications.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Hormones and genes affect hair growth and male baldness.

A new mutation in the ST14 gene causes a rare skin and hair disorder in a specific family.

Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.

A 28-year-old man with type 1 diabetes had skin and hair issues due to zinc deficiency.

The conclusion is that maintaining blinding in clinical trials is crucial for reliable results.