Type II Vitamin D Dependent Rickets: A Case Report

January 1970 in “ Journal of Nepal Paediatric Society ”

Kalpana Karmacharya Malla, T Malla, Chandan Kumar Shaw, A Thapalial

alopecia scalp alopecia body alopecia 1,25-dihydroxyvitamin D parathyroid hormone hair loss vitamin D

TLDR Hair loss can be a key sign of a rare type of rickets when vitamin D treatment doesn't work and advanced tests aren't available.

The document reports on a case of Vitamin D-dependent rickets Type II, an uncommon autosomal recessive disorder, and highlights the association of alopecia with the disease. The case involves a child diagnosed with this condition, and the report emphasizes that alopecia, either of the scalp or body, can be a significant indicator for this syndrome, especially when rickets is resistant to treatment and there is a lack of facilities to measure 1,25-dihydroxyvitamin D (1,25(OH)2 D) and parathyroid hormone levels. The document suggests that in the absence of advanced diagnostic capabilities, the presence of alopecia may serve as an important diagnostic clue for this rare form of rickets.

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Research cited in this study

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research Vitamin D-Dependent Rickets Type II with Alopecia: Two Case Reports and Review of the Literature

31 citations, September 2003 in “International Journal of Dermatology”

Vitamin D-dependent rickets Type II causes bone problems and hair loss, and doesn't improve with Vitamin D treatment.

research Two Siblings With Vitamin-D-Dependent Rickets Type II: No Recurrence Of Rickets For 14 Years After Cessation Of Therapy

47 citations, October 1989 in “European Journal of Pediatrics”

Two siblings stayed rickets-free for 14 years after stopping treatment.

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