Behcet's Disease and Complex Aphthosis

    Joseph L. Jorizzo
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    TLDR Aging affects hair density and skin health, and Behcet's disease, a complex condition with no specific test, involves sores and systemic issues, treated with various medications.
    The document provides an overview of various dermatological conditions affecting the elderly, including skin care after age 40, genital skin diseases, nail plate changes, hair and scalp diseases, and cutaneous mycoses. It highlights that aging and photoaging negatively impact hair density, and that diseases like heliodermatosis and epithelial neoplasms are severe in the elderly, especially with long-duration androgenic alopecia. The document also discusses Behcet's disease, a complex multisystem disease without a definitive laboratory test for diagnosis, characterized by oral and genital aphthae, pustular vasculitic cutaneous lesions, and other systemic manifestations. Treatment options for mucocutaneous disease include topical agents, oral colchicine, dapsone, or thalidomide, while systemic corticosteroids and immunosuppressive drugs are used for ocular and systemic disease. Complex aphthosis involves the presence of multiple oral aphthae or the occurrence of oral and genital aphthae, with evaluation and treatment similar to Behcet's disease. The document does not provide specific numbers of people involved in any studies, as it appears to be a summary of various conditions and treatments rather than a report on a single study.
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