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Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Significant progress and collaborations in stem cell research and regenerative medicine were made, including advancements in hair growth, cancer therapies, and treatments for neurological disorders.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

A JAK inhibitor improved both severe hair loss and chronic skin disease in one patient.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Natural products might be safe, effective, and affordable treatments for hair loss.

Gefitinib and Sasam-Kyeongokgo together significantly reduce cancer growth and improve immune response in mice.

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

Zebrafish are useful for studying and developing treatments for human skin diseases.

Paclitaxel is an effective cancer drug with side effects and potential new uses beyond cancer.

Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

New treatments for alopecia areata show promise, but more research is needed to confirm their effectiveness.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

The new matrix improves skin regeneration and graft performance.

Human sweat glands have a type of stem cell that can grow well and turn into different cell types.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Bio-pulsed stimulation increases production of beneficial vesicles from bird stem cells that improve skin and hair cell functions.

Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.

Cellular and immunotherapies show promise for healing chronic wounds but need more research.

In September 2016, there were major advancements and promising clinical trials in stem cell research and regenerative medicine.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.