2 citations,
December 2022 in “Pharmaceutics” The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.
57 citations,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
45 citations,
August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
12 citations,
January 2009 in “Stembook” Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
10 citations,
August 2021 in “Frontiers in cell and developmental biology” Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.
6 citations,
June 2022 in “Frontiers in Bioengineering and Biotechnology” The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
2 citations,
October 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” AIRE deficiency causes hair loss similar to alopecia areata in mice.
1 citations,
January 2019 in “Journal of Dermatology and Dermatologic Surgery” Stem cell therapy shows promise for hair loss treatment, but more research is needed to confirm its effectiveness.
September 2023 in “Nature Communications” Immune cells are essential for skin regeneration using biomaterial scaffolds.
KY19382 helps to regrow hair and create new hair follicles.
January 2020 in “Egyptian Journal of Dermatology and Venereology” People with alopecia have shorter hair follicles and more c-kit, a stem cell factor receptor, which could predict how the condition progresses.
Targeting CXXC5 and GSK-3β may help treat male pattern baldness.
May 2024 in “Regenerative Therapy” Dendrobium officinale polysaccharide helps hair growth by activating the WNT signaling pathway.
11 citations,
October 2017 in “International Journal of Molecular Sciences” A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.
98 citations,
June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” A cluster of sulfur-rich hair protein genes was found on chromosome 17.
March 2010 in “Ejc Supplements” CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.
January 2015 in “Journal of Cytology and Histology” Hair loss in Androgenetic Alopecia is not caused by damage to follicular stem cells.
4 citations,
January 2017 in “Journal of veterinary medical science” A dog had a rare skin tumor called desmoplastic tricholemmoma.
6 citations,
July 2018 in “Advances in Clinical and Experimental Medicine” Different body parts have varying levels of certain hair follicle markers.
54 citations,
January 2009 in “British Journal of Dermatology” Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
14 citations,
January 2011 in “Journal of Cutaneous Pathology” CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.
2 citations,
March 2018 in “Biotechnology Letters” Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
10 citations,
December 2015 in “International Journal of Dermatology” CK 15, follistatin, and Bmi-1 can help differentiate basal cell carcinoma from squamous cell carcinoma.
May 2020 in “Archives of Medical Science” Men with androgenetic alopecia have lower levels of certain proteins and more cell damage.
120 citations,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
2 citations,
April 2021 in “FEBS open bio” Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
April 2018 in “Journal of Investigative Dermatology” The conclusion introduces a new way to classify skin cysts using their shape and genetic markers.
74 citations,
October 1998 in “Journal of biological chemistry/The Journal of biological chemistry” The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
14 citations,
February 2021 in “Experimental Dermatology” Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
11 citations,
September 2016 in “Journal of virological methods” Rabies virus was found in specific skin cells of rabid dogs' muzzles, suggesting these cells could help diagnose rabies.