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The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

Finasteride in male rats causes liver and metabolic issues in their offspring.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.

Tiny particles from skin cells can help activate hair growth.

Porphyra-334 may help reduce wrinkles and promote hair growth.

Genes linked to wool fineness in sheep have been identified.

New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.

The document explains how male reproductive hormones work and affect the body.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Certain drugs that block specific enzymes can help treat prostate diseases.

Adrenal disorders can cause lasting brain and behavior issues in children.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

BRG1 is essential for skin cells to move and heal wounds properly.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Potential new drugs for treating PCOS were identified.