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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Potential new drugs for treating PCOS were identified.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

A group has developed therapies that show promise for treating cancer and various other conditions.

A new method accurately measures nine specific hormones in human blood.

Certain drugs change freshwater snail shells to a "banana" shape.

Certain drugs that block specific enzymes can help treat prostate diseases.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.