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Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Certain drugs that block specific enzymes can help treat prostate diseases.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

More research is needed to understand how testosterone is maintained in adult males.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Borneol Essential Oil could be a natural and safe acne treatment.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Finasteride in male rats causes liver and metabolic issues in their offspring.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Editing the FGF5 gene in sheep increases fine wool growth.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Aromatase inhibitors cause male pattern hair loss in women.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The document explains how male reproductive hormones work and affect the body.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

The document concludes that effectively managing PCOS requires a multifaceted approach.