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Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

SHBG may be a useful early indicator and treatment target for PCOS.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

CIP/KIP proteins help stop cell division and support hair growth.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Hormones and genes affect hair growth and male baldness.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Two gene variations, rs6493497 and rs7176005, may be linked to female hair loss in Chinese people.

Testosterone is crucial for development, growth, and various body functions in mammals.

Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Testosterone reduces heart damage and inflammation after injury.