124 citations,
August 1994 in “Journal of Investigative Dermatology” Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.
84 citations,
March 2004 in “Veterinary Dermatology” Cyclosporin is effective in treating dog skin diseases and has fewer side effects compared to other treatments.
59 citations,
February 2003 in “Veterinary Dermatology” Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
57 citations,
June 2003 in “American Journal of Physiology-cell Physiology” Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
45 citations,
September 2001 in “Journal of Investigative Dermatology” Cyclosporin A promotes hair cell growth and affects protein kinase C levels.
36 citations,
January 2006 in “Veterinary Dermatology” Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.
24 citations,
September 2001 in “Journal of Dermatological Science” Cyclosporin A helps damaged hair follicles regrow hair quickly.
16 citations,
July 1989 in “British journal of dermatology/British journal of dermatology, Supplement” Topical cyclosporin A doesn't work for alopecia totalis because it doesn't penetrate the skin well.
12 citations,
November 1996 in “Australasian journal of dermatology” A kidney transplant patient on cyclosporin experienced unexpected severe hair loss, which improved with treatment adjustments.
7 citations,
February 2014 in “Talanta” Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.
5 citations,
February 2008 in “Experimental Dermatology” Cyclosporin A promotes hair growth in mice and increases a protein linked to hair growth, but it may not work the same way in humans.
3 citations,
March 2014 in “Journal of Industrial Microbiology & Biotechnology” Scientists found a new gene in a bacterium that can modify an immunosuppressant drug, potentially helping to treat hair loss.
April 2023 in “Journal of Investigative Dermatology” Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.
January 2003 in “Journal of Clinical Dermatology” Cyclosporin promotes hair growth by boosting cell growth and reducing cell death.
August 1994 in “Journal of dermatological science” Cyclosporin A and FK506 can start new hair growth in mice, but ascomycin and rapamycin cannot.
July 2008 in “British Journal of Dermatology” Cyclosporin doesn't stop hair loss.
15 citations,
November 1997 in “Australasian Journal of Dermatology” A combination of oral cyclosporin and PUVA treatment worked well for a severe skin condition called generalized pustular psoriasis.
10 citations,
July 1994 in “Journal of Dermatological Science” Cyclosporin extends hair growth in mice, but high-dose corticosteroids block this effect.
1 citations,
November 2001 in “British Journal of Dermatology” Oral cyclosporin doesn't stop hair loss.
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.
January 2003 in “Reactions Weekly” Lowering the dose of cyclosporin caused hair loss that didn't improve even when the dose was increased again.
89 citations,
October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
85 citations,
April 2007 in “Dermatologic Clinics” Some drugs can cause hair loss, change hair color and shape, or increase hair growth, and treatment may involve stopping the drug or using specific hair growth treatments.
49 citations,
November 1992 in “Archives of dermatology” Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.
21 citations,
October 2009 in “Biochemical Engineering Journal” Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
5 citations,
May 2004 in “International Journal of Cosmetic Science” Versican is important for hair growth and could help find new hair regrowth treatments.
3 citations,
February 2021 in “Experimental dermatology” Dermal papilla microtissues could be useful for initial hair growth drug testing.
1 citations,
October 2018 in “InTech eBooks” Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
November 2022 in “Journal of Investigative Dermatology” The medicine Cyclosporin A might cause excessive hair growth by reducing a protein that controls hair growth.
October 2018 in “InTech eBooks” The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.