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    Did you mean Calcineurin Inhibitors?
    Glossary Calcineurin Inhibitors

    medications that suppress immune response by blocking calcineurin activity

    Calcineurin inhibitors (CNIs) are a class of medications that suppress the immune system by blocking the activity of calcineurin, a protein involved in activating T-cells. They are commonly used to prevent organ transplant rejection and to treat autoimmune diseases. In dermatology, CNIs like tacrolimus and pimecrolimus are used topically to manage conditions such as atopic dermatitis and certain types of alopecia, as they help reduce inflammation and immune response in the skin.

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    Research 10 of 831

    1. The Many Faces of Calcineurin Inhibitor Toxicity—What the FK? Advances in chronic kidney disease · 2020 · 97 citations
    2. Endocrine effects of long-term calcineurin inhibitor use in solid organ transplant recipients European Journal of Endocrinology · 2025 · 7 citations
    3. Update on the use of topical calcineurin inhibitors in cutaneous lupus erythematosus Biologics: Targets & Therapy · 2011 · 9 citations
    4. Scalp atrophy secondary to steroid use in patients with scarring alopecia: are topical steroids superior to topical calcineurin inhibitors? International Journal of Dermatology · 2023 · 1 citations
    5. Calcineurin/Nuclear Factor of Activated T-Cell Pathway in Cutaneous Squamous Cell Carcinoma International journal of dermatology and venereology · 2019
    6. Effect of immunosuppressive ppiase inhibitors, cyclosporin A, FK506, ascomycin and rapamycin on hair growth initiation Journal of dermatological science · 1994
    7. British Association of Dermatologists’ guidelines for the management of alopecia areata 2012 British Journal of Dermatology · 2012 · 218 citations
    8. Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas Clinics in Dermatology · 2008 · 104 citations
    9. Vitiligo - Part 2 - classification, histopathology and treatment Anais Brasileiros de Dermatologia · 2014 · 78 citations
    10. Safety of dermatologic medications in pregnancy and lactation Journal of The American Academy of Dermatology · 2014 · 73 citations
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