Cyclosporin Interaction in a 35-Year-Old Man with Atopic Dermatitis and Alopecia Areata

    January 2003 in “ Reactions Weekly ”
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    TLDR Lowering the dose of cyclosporin caused hair loss that didn't improve even when the dose was increased again.
    A 35-year-old man developed alopecia areata after his dose of cyclosporin was reduced from 5 mg/kg/day to 3.5 mg/kg/day, which he was taking for atopic dermatitis. Initially, he experienced telogen effluvium, which quickly progressed to alopecia areata within 5 days. When cyclosporin treatment was stopped, his atopic dermatitis worsened, but there was no change in his alopecia areata. Even after reintroducing cyclosporin at a dose between 3.5 and 5 mg/kg/day, his alopecia areata remained unchanged. The patient's final outcome was not reported in the document.
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