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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Apple polyphenols, especially from unripe apples, can help prevent cells from turning into fat cells.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Activating TRPV3 channels stops hair growth by killing hair follicle cells.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

Adding celecoxib to chemotherapy improves survival and quality of life for gastric cancer patients with positive COX-2.

Marine-derived saccharides may help reduce aging effects on skin and hair by promoting cell growth and collagen production.

Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.

Nerve growth factor helps cashmere goat hair cells grow and is more active during the hair growth phase.

Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.

Glycyrrhizic acid may help reduce unwanted hair growth.

Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Cyclic nucleotide-gated channels are crucial for proper root hair growth and calcium balance in plants.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

The plant hormone auxin activates the TOR pathway, affecting gene expression related to growth and cell size.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.

Hair follicle regeneration may slow tumor growth.