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Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

The skin microbiome helps heal wounds and can be targeted to improve healing.

Immune cells are essential for early hair and skin development and healing.

Alk1 in specific cells is crucial for proper nerve branching and hair function.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

ILC1-like cells can cause alopecia areata by attacking hair follicles.

Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.

Mint water extract boosts protective enzymes in skin cells.

Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.

The role of γδT-cells in causing alopecia areata remains unclear.

Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

New materials and methods could improve skin healing and reduce scarring.

Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.

Targeting Vδ1+T-cells may help treat alopecia areata.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Hair follicles help attract immune cells to the skin during stress.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Stem cells can help other stem cells by producing supportive factors.

Human dermal γδT-cells respond to stress in hair follicles, contributing to hair loss.

The secretome from mesenchymal stem cells shows promise for treating skin conditions and improving skin and hair health, but more research is needed.

Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.