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This study found no significant difference in CUX1 core promoter methylation levels between different lambskin patterns in Hu sheep, suggesting other mechanisms influence CUX1 expression related to hair follicle development.

This study suggests that the transcription factors SP1 and KROX20 regulate CUX1 gene's effect on the proliferation of ovine dermal papilla cells in vitro.

This study found that mice with a mutant CDP/Cux protein lacking the homeodomain showed severely impaired growth, high postnatal mortality, and reduced fertility, highlighting CDP/Cux's role in developmental regulation.

This study found that overexpression of the CUX1 protein promotes proliferation of Hu sheep dermal papilla cells and affects key genes in the Wnt/β-catenin signaling pathway.

In this study, researchers used genetic data from over 52,000 men to identify over 250 genetic loci associated with severe hair loss and developed a predictive algorithm for determining hair loss risk.

This study observed significant differences in hair and cashmere properties among three goat breeds in Southwest China, noting better quality cashmere in Inner Mongolia cashmere goats and their crossbreed compared to Dazu black goats.

This study on Dorper sheep identified important genetic factors influencing hair follicle development, finding that expression patterns and genes like DBI, FZD3, and ZDHHC21 play a crucial role in wool shedding, which could help improve understanding of mammalian skin-related traits and human hair advancement.

This study identified changes in transcription factor gene expression across various signaling pathways during inner ear hair cell regeneration in birds, revealing patterns and potential new pathways for future investigation.

This study found that Cutl1 mutant mice experienced retarded lung differentiation and abnormal hair follicle morphogenesis, indicating the vital role of CDP in lung development and hair follicle cell-lineage specification.

In this review, an association was reported between early-onset androgenetic alopecia and several health conditions like obesity and cardiovascular disease, with genetic and therapeutic research ongoing to improve treatment.

In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.

This study in cashmere goats found that DNA methylation levels were lower during hair follicle differentiation compared to induction, suggesting it plays a critical role in gene regulation for hair morphogenesis.

In this study, male-pattern baldness was strongly associated with a higher risk of keratinocyte cancers, particularly squamous cell carcinoma and melanoma, likely due to increased sun exposure on the scalp rather than androgen levels.

This study used single-cell RNA sequencing to map the cellular composition of sheep hair follicles, revealing differentiation pathways and potential molecular mechanisms for wool curvature, which may inform sheep breeding.

This study identified key genes and pathways involved in the seasonal hair cycle regulation of yak, uncovering molecular mechanisms that may aid in understanding their adaptation to alpine environments.

Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.

This study explored a mother and daughter with loose anagen hair syndrome linked to wooly hair, identifying an intronic variant in the KRT71 gene that affects hair keratin splicing, thus broadening the spectrum of KRT71-related disorders.

This study found that miRNAs increase and target mRNAs and lncRNAs decrease from the anagen to telogen phase in mouse hair follicles, and these ceRNA networks may play a role in hair follicle cycling.

This study found that synchronized signals in the microenvironment regulate stem cell lineage choices in hair follicles by influencing chromatin dynamics during regeneration.

This study identified key long non-coding RNAs and mRNAs involved in primary wool follicle induction in carpet wool sheep, emphasizing their roles in hair follicle development and skin processes.

This study found that vitamin C deficiency in SMP-30/GNL-KO mice affected gene expression related to hair growth and cell growth, resulting in delayed hair growth compared to those with adequate vitamin C.

This study identifies a polygenic basis for atypical recurrent flank alopecia in Cesky Fousek dogs through genome-wide association analysis and gene expression profiling, highlighting several metabolic pathways involved in the condition.

This review highlights the critical role of microRNAs in regulating hair follicle biology, significantly impacting wool and cashmere development by modulating gene expression and signaling pathways in sheep and goats.

This study examined the cytodifferentiation stage of hair follicle development in cashmere goats, identifying nine cell populations and key regulatory pathways, including transcription factors and keratin genes, that may influence fiber quality and inform breeding strategies.

This review discusses the integration of omics analyses in androgenetic alopecia research, reporting no new clinical results but suggesting that collaborative multi-omics studies may enhance understanding of AGA's pathomechanisms.

In this study, researchers analyzed miRNA and gene expression in the hair follicles of FMD during different hair cycle stages, identifying differential expression patterns and key pathways involved in hair follicle development and growth.

This study found significant differences in mRNA and miRNA expression between yak dermal papilla cells and epidermal hair matrix cells, suggesting important roles for these molecules in hair follicle development.

This study reveals that long non-coding RNAs influence cashmere fiber traits in goats by interacting with target genes involved in pathways affecting fiber diameter and color.

In this study, using scRNA-seq, researchers detailed the gene expression and cell differentiation processes in goat fetal horn buds, identifying crucial roles for dermal and epithelial cells in horn initiation and highlighting potential genetic factors involved in horn morphogenesis.

This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.