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The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Most dogs have hair whorls on their chest and limbs, with shelter dogs and short-haired dogs having more chest whorls.

Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.

Understanding how fetal wounds heal could help improve healing in adults.

Dermatologists diagnose and manage melanoma more effectively than general practitioners.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Advancements in hair biology include new treatments and tools for hair growth and alopecia.

The most common causes of hair loss in children in South-East Nigeria are fungal infections and alopecia areata.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

ILK and ELMO2 help cells move and stick together, important for wound healing and hair growth.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

Alefacept may effectively treat severe lichen planus, with patients showing significant improvement and no side effects.