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Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

Adenosine helps human hair grow and prevents hair loss by targeting specific cells.

Stem cell therapy is a promising approach for hair regrowth despite potential side effects.

Aminoguanidine increases a specific growth signal in stored hair grafts, which may help them survive better after being transplanted.

Aminoguanidine increases VEGF in stored hair micrografts, potentially improving their viability after transplant.

Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.

Growth factors are crucial for hair development and could help treat hair diseases.

Advanced human skin models improve drug development and could replace animal testing.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Using 2% minoxidil for baldness treatment might cause vision distortion due to fluid build-up under the retina.

The Hairless gene is crucial for healthy skin and hair growth.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.

Hair follicle regeneration may slow tumor growth.

Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.

Skin cell-derived vesicles can help heal skin injuries effectively.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

The engineered skin substitute helped grow skin with hair on mice.

Future research should focus on making bioengineered skin that completely restores all skin functions.