1 citations
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July 2025 in “PubMed” This pilot study found that cord blood platelet-rich plasma treatment was safe and improved symptoms and sexual function in women with vulvar lichen sclerosus after standard topical corticosteroid treatment.
1 citations
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June 2021 in “Problems of Cryobiology and Cryomedicine” In this study on rats, CBF injections demonstrated significant wound healing effects and improved recovery after skin cryoablation, similar to the effects observed with Actovegin.
This review explores the clinical applications of platelet rich plasma therapies across several fields and suggests potential future research directions for cord blood platelet rich plasma.
30 citations
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May 2019 in “Medicinal Research Reviews” This review discusses molecular and cellular strategies to improve muscle and skin regeneration and reduce scarring after cleft lip repair, offering potential benefits for function and aesthetics.
December 2025 in “Journal of 108 - Clinical Medicine and Phamarcy” This study found differential expression of growth factors and cytokines in umbilical cord blood-derived platelet-rich plasma, with the highest concentrations observed in the B blood type, but also noted weak correlations with ABO blood groups, suggesting other influencing factors.
November 2025 in “Archives of Dermatological Research” This study found that Limelight (CB-EVs) exosomes significantly promoted hair elongation ex vivo without cytotoxicity, suggesting potential as a safe and effective hair growth therapy.
This review discusses the use of umbilical cord blood in regenerative medicine, focusing on collection, banking processes, and ethical considerations, without presenting new clinical results.
May 2017 in “Journal of the American Academy of Dermatology” Modified stem cells can improve hair growth.
21 citations
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January 2018 in “The Korean Journal of Physiology and Pharmacology” This study found that human umbilical cord blood mesenchymal stem cells promoted hair growth by advancing anagen onset and increasing hair follicle regeneration in an in vivo model.
19 citations
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May 2020 in “Cells” This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.
12 citations
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December 2019 in “International Journal of Molecular Medicine” This study found that human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) significantly prevented hair loss induced by dexamethasone in a mouse model and enhanced cell proliferation in human hair follicle cells, suggesting a protective effect against stress-related hair loss.
10 citations
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August 2023 in “Clinical Nutrition” This study found that exposure to certain elements during pregnancy, measured in maternal hair, was associated with increased risk of gestational diabetes and potential impacts on infant neurodevelopment, with elements like Ta, Re, and Se posing the highest risk for gestational diabetes.
January 2026 in “Asian Journal of Pharmaceutical and Clinical Research” This review discusses the potential of umbilical cord blood and umbilical cord-derived stem cells in treating various chronic diseases by highlighting their regenerative abilities and ethical advantages as well as the translational challenges and clinical implications.
September 2014 in “Genes and Cells” This study observed that using transfected human cord blood cells enhanced skin wound healing in rats by promoting angiogenesis and earlier termination of proliferation compared to untransfected cells.
January 2019 in “Journal of Clinical Dermatology” This study found that a hair tonic containing a human umbilical cord blood mesenchymal stem cell-derived conditioned medium significantly increased hair density, thickness, and growth rate in patients with androgenetic alopecia.
May 2014 in “Transfusion and Apheresis Science” The study found that the quality of cord blood units remains consistent before freezing and after thawing, indicating that attached tube segments reliably represent the graft's properties.
January 2019 in “대한피부과학회지” In this study, a hair tonic containing human umbilical cord blood mesenchymal stem cell-derived conditioned medium significantly increased hair density, thickness, and growth rate in patients with androgenetic alopecia.
48 citations
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July 2019 in “International Journal of Biological Macromolecules” This study found that a newly developed injectable hydrogel combined with human umbilical cord-mesenchymal stem cells significantly accelerated wound healing and reduced inflammation in full-thickness cutaneous wounds.
55 citations
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April 2015 in “BMC medicine” This study found that the Stem Cell Educator therapy improved hair regrowth and quality of life in patients with severe alopecia areata by restoring immune balance and protecting hair follicles from autoimmune damage.
1 citations
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July 2019 in “Journal of Dermatology and Dermatologic Surgery” This review discusses the potential of stem cell therapies for regenerating hair in nonautoimmune hair loss and calls for more studies to evaluate their efficacy.
June 2026 in “Scholarly review .” This review discusses the impact of endocrine-disrupting chemicals on pediatric health, linking them to various disorders, and calls for improved biomonitoring strategies and precautionary policies.
May 2022 in “Clinical Epigenetics” This study found that maternal early-pregnancy serum ferritin concentrations were associated with lower DNA methylation levels at specific CpG sites in cord blood, with some associations persisting into childhood.
48 citations
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March 2021 in “Frontiers in Cell and Developmental Biology” This review discusses the use of human mesenchymal stem cells (hMSCs) for treating skin diseases and suggests they show promise for improving conditions like wounds and scleroderma, but more research is needed due to varied study designs and endpoints.
12 citations
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February 2025 in “Scientific Reports” This study found that extracellular vesicles derived from mesenchymal stem cells and umbilical cord blood plasma enhanced wound healing and reduced scar formation in mice, suggesting their potential as therapeutic agents for skin repair.
8 citations
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October 2022 in “Regenerative Therapy” This review discusses regenerative medicine approaches for treating alopecia, including mesenchymal stem cell therapies and platelet-rich plasma, but reports no new clinical results, emphasizing the need for further study.
5 citations
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January 2005 in “Cytotherapy” This meeting in Heidelberg highlighted diverse contributions on stem cell research, including pre-clinical and clinical applications, but reported no new experimental results.
April 2026 in “Journal of Exercise Rehabilitation” This report describes a case where a woman's hair loss following COVID-19 vaccination improved after treatment with autologous CD34+ hematopoietic progenitor cells and umbilical cord blood-derived mesenchymal stem cells, with no significant adverse effects observed over the 12-week treatment period.
September 2024 in “British journal of surgery” In this study, autologous stem cell therapy was associated with a 29% increase in hair density in androgenetic alopecia patients over six months, suggesting potential for further investigation.
July 2024 in “British journal of surgery” This review reports that regenerative medicine, such as autologous stem cell micrografting and Rigenera®, may significantly improve hair density in individuals with androgenetic alopecia, highlighting its potential as a future therapeutic option that addresses current treatment limitations.
February 2024 in “Plastic and Reconstructive Surgery – Global Open” This systematic review found that both cellular and acellular stem cell-based therapies are safe and able to improve hair regeneration and density in patients with androgenic alopecia, although some results may be temporary.