First Use of Cord Blood Platelet-Rich Plasma in the Treatment of Vulvar Lichen Sclerosus: A Preliminary Study Towards a Randomized Controlled Trial.

    July 2025 in “ PubMed ”
    Veronica Boero, Carlotta Caia, Giulia Emily Cetera, Elisa Pesce, Serena Uccello, Stefania Villa, Tiziana Montemurro, Larysa Mykhailova, Camilla Erminia Maria Merli, Ermelinda Monti, Flavia Filippi, Paolo Vercellini, Daniele Prati
    Studysummary This pilot study found that cord blood platelet-rich plasma treatment was safe and improved symptoms and sexual function in women with vulvar lichen sclerosus after standard topical corticosteroid treatment. Our plain-language summary of this paper — not a Tressless recommendation.
    This preliminary study suggests that cord blood platelet-rich plasma (CB-PRP) could be a promising treatment for vulvar lichen sclerosus (VLS). The findings indicate that CB-PRP is safe and may lead to improvements in symptoms and sexual function for individuals with VLS. Further research, such as a randomized controlled trial, is needed to confirm these results.
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