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      Regeneration of Skin Appendages and Nerves: Current Status and Further Challenges

      research Regeneration of skin appendages and nerves: current status and further challenges

      71 citations , February 2020 in “Journal of Translational Medicine”
      This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.
      Prostate Cancer Prevention

      research Prostate cancer prevention

      71 citations , September 2007 in “Cancer”
      This review discusses various prostate cancer prevention strategies and reports no new clinical results; the authors highlight the need for ongoing research in this area.
      Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

      research Drug discovery for alopecia: gone today, hair tomorrow

      70 citations , February 2015 in “Expert Opinion on Drug Discovery”
      This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.

      research Beyond Expectations

      70 citations , January 2014 in “International review of cell and molecular biology”
      This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.
      The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair

      research The role of nuclear hormone receptors in cutaneous wound repair

      68 citations , December 2014 in “Cell Biochemistry and Function”
      This review examines the role of nuclear hormone receptors in skin wound repair processes and reports no new clinical results, highlighting the importance of their interaction with skin cells for effective healing.
      Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease

      research Local heroes or villains: tissue-resident memory T cells in human health and disease

      67 citations , January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology”
      This review discusses the dual role of tissue-resident memory T cells in providing immune protection against infections and cancer and contributing to autoimmune skin disease pathology, without presenting new experimental results.
      Toll-Like Receptor Function in Acute Wounds

      research Toll-Like Receptor Function in Acute Wounds

      65 citations , May 2017 in “Advances in wound care”
      This review discusses the role of Toll-like receptors in wound healing and highlights their potential therapeutic value but notes that their role in human wound healing and chronic wounds is not well understood.
      The Role of Macrophages in Skin Homeostasis

      research The role of macrophages in skin homeostasis

      65 citations , February 2017 in “Pflügers Archiv - European Journal of Physiology”
      This review examines the roles of macrophages and Langerhans cells in skin homeostasis and suggests that understanding these functions can aid in developing therapies for skin and hair regeneration, but it reports no new research findings.
      Near Infrared Light Therapy of Eye Diseases: A Review

      research Near Infrared (NIR) Light Therapy of Eye Diseases: A Review

      60 citations , November 2020 in “International Journal of Medical Sciences”
      This review highlights the potential of near-infrared light therapy to improve metabolic, antioxidant, and cognitive functions without adverse effects, and supports its use for visual and neurological conditions through molecular and cellular mechanisms, as reported in this source.
      Nanotechnology in Dermatology

      research Nanotechnology in Dermatology

      60 citations , January 2014 in “Anais Brasileiros De Dermatologia”
      This article discusses the foundational concepts of nanotechnology and its contributions to dermatology and medicine, but does not present new research findings.
      Dynamic Signals for Hair Follicle Development and Regeneration

      research Dynamic Signals for Hair Follicle Development and Regeneration

      60 citations , July 2011 in “Stem Cells and Development”
      This review discusses recent findings on hair follicle morphogenesis and regeneration, focusing on molecular signals and stem cells, and suggests that understanding these processes may aid in developing new strategies for wound healing.
      Apoptosis and Cutaneous Biology

      research Apoptosis and cutaneous biology

      60 citations , June 1997 in “Journal of The American Academy of Dermatology”
      This review discusses the basic biology of apoptosis and its relevance to skin diseases, without presenting new research findings.
      Wnt Signaling and Aging-Related Heart Disorders

      research Wnt Signaling and Aging-Related Heart Disorders

      59 citations , November 2010 in “Circulation Research”
      This review discusses the potential role of Wnt signaling in aging-related heart diseases and reports no clinical results.
      The Role of Smads in Skin Development

      research The Role of Smads in Skin Development

      59 citations , March 2008 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This review examines the roles of Smad-4 and Smad-7 in hair follicle differentiation and development through BMP signaling and TGFβ/Activin/BMP pathway inhibition but reports no new experimental results.
      Choreographing Immunity in the Skin Epithelial Barrier

      research Choreographing Immunity in the Skin Epithelial Barrier

      57 citations , March 2019 in “Immunity”
      This review discusses the roles of immune responses and cells in skin health and disease, emphasizing recent insights into their mechanisms and potential therapeutic applications, but presents no new experimental results.
      Absorption Sites of Orally Administered Drugs in the Small Intestine

      research Absorption sites of orally administered drugs in the small intestine

      55 citations , September 2017 in “Expert Opinion on Drug Discovery”
      This review examines the main absorption sites and influencing factors for orally administered drugs, highlighting variables such as solubility and gastrointestinal conditions that affect drug absorption in the small intestine and the development of effective drug delivery systems.
      P63: A Crucial Player In Epithelial Stemness Regulation

      research p63: a crucial player in epithelial stemness regulation

      54 citations , October 2023 in “Oncogene”
      In this review, the researchers detailed how the p63 transcription factor influences epithelial stem cell activities such as self-renewal, differentiation, and proliferation, highlighting the role of TAp63 and ΔNp63 isoforms in both normal tissue development and cancer pathogenesis.