61 citations
,
February 2001 in “American Journal of Obstetrics and Gynecology” This study suggests that polycystic ovary syndrome symptoms are uncommon among women with metabolic syndrome, indicating it may represent only a specific subset within the broader context of metabolic syndrome.
57 citations
,
September 2005 in “International Journal of Dermatology” This study reported that chemical relaxants and hair styling practices were associated with scarring hair loss, particularly among women with central centrifugal cicatricial alopecias.
32 citations
,
December 2017 in “International Journal of Molecular Sciences” This review suggests that decreased serum 25-hydroxyvitamin D levels may play a role in different types of non-scarring alopecia, but further studies are needed to explore vitamin D supplementation as a therapeutic option.
28 citations
,
January 2021 in “Parkinsonism & related disorders (Online)/Parkinsonism & related disorders” This article reviews skin disorders in Parkinson's disease, highlighting the potential of skin studies and stem cell research to advance understanding and treatment of the neurodegenerative disorder, without presenting new results.
24 citations
,
June 2018 in “Reviews in endocrine and metabolic disorders” This review discusses the epidemiology, clinical manifestations, and pathogenesis of autoimmune skin diseases and their associations with thyroid diseases, reporting no new clinical results.
15 citations
,
November 2023 in “Immunity & ageing” This review highlights the role of the receptor TLR4 in cellular aging and age-related diseases, suggesting it as a potential therapeutic target due to its contribution to persistent inflammation and symptom regulation in these conditions.
6 citations
,
May 2015 in “Clinics in Dermatology” This review highlights the evolving understanding of PCOS, emphasizing the dermatologist's role in early diagnosis and management of systemic implications, while acknowledging that it reports no new clinical results.
4 citations
,
February 2018 in “Journal of Investigative Dermatology” This study suggests that thermal imaging may aid in diagnosing cellulitis, potentially improving patient care, although its applicability to certain cases requires further investigation.
3 citations
,
July 2015 in “European Journal of Dermatology” This abstract discusses the role of advanced glycation end-products in aging-related skin damage, but does not provide new findings on their impact on alopecia.
September 2023 in “Frontiers in medicine” This review suggests that the mTOR signaling pathway may play a significant role in hair follicle health by influencing the effects of Vitamin D receptor deficiency, potentially contributing to hair follicle damage and related hair loss conditions.
October 2020 in “Indian journal of forensic medicine and toxicology” This review discusses the link between polycystic ovary syndrome and periodontal disease and emphasizes the need for further studies to clarify their association, but it reports no new clinical results.
October 2018 in “InTech eBooks” This research suggests that mouse mutants and genomics can help study hair biology and epithelial differentiation by focusing on the role of the Foxn1 gene.
This study found that type XVII collagen is crucial for regulating epidermal cells' proliferation in mice and may be a promising target for anti-aging skin treatments.
153 citations
,
June 2015 in “GenomeBiology.com” This study found that both genome-wide screening methods identified the VTRNA2-1 epiallele as highly responsive to environmental influences, suggesting a link between early embryonic environment, epigenetic changes, and human disease.
55 citations
,
July 2013 in “Dermatologic therapy” This review explores the impact of various medications on male fertility, highlighting reversible negative effects from methotrexate, finasteride, and ketoconazole, while reporting no adverse fertility effects for oral retinoids and certain immunosuppressants.
17 citations
,
February 2004 in “PubMed” This review discusses symptom-driven treatment approaches for PCOS, focusing on ovulation induction, androgen reduction, and weight management, and reports recent advances like recombinant FSH and GnRH-agonist protocols without providing new clinical results.
16 citations
,
April 1978 in “Genetics Research” This study found that asebic mice exhibit abnormal sebaceous gland differentiation and insufficient sebum production due to defective regulation of cell processes, despite possessing normally developing sebaceous glands initially.
7 citations
,
April 2013 in “Animal Production Science” This study found that manipulating maternal cortisol levels during pregnancy altered Merino sheep wool characteristics, increasing fibre length and reducing crimp frequency in the offspring.
5 citations
,
October 2012 in “Journal of Midwifery & Women's Health” This article reviews infertility diagnosis and initial management for advanced practice clinicians, emphasizing the role of midwives and advanced practice nurses, but reports no new clinical findings.
2 citations
,
January 1979 in “Yearbook of English studies” This article discusses the perceived shortcomings of nineteenth-century British drama in addressing contemporary ideas, questioning its literary vitality beyond stage performance, and reports no new results.
1 citations
,
January 2022 in “Journal of experimental and clinical medicine” This review examines the relationship between glycation, insulin resistance, and PCOS, discussing various treatments and highlighting M. oleifera and S. platensis as potential therapeutic agents, but reports no new clinical results.
September 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study mapped the development of the human pilosebaceous unit in prenatal scalp skin using multi-modal analysis, finding that epithelial-mesenchymal interactions guide cellular fate and validated tissue-patterning through a hair-bearing skin organoid model.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
September 2023 in “Middle East Fertility Society Journal” This study found that nicotine may have a therapeutic role in mitigating the exacerbation of infertility conditions connected with alpha-synuclein-related Parkinson’s disease through molecular interactions identified via pathway analysis.
January 1997 in “Elsevier eBooks” This review discusses the development and types of hair and nails as skin appendages and reports no new research findings.
162 citations
,
August 2004 in “Journal of Investigative Dermatology” This study suggests that stress negatively affects hair growth by inducing inflammation and early hair cycle transitions in mice, which might inform strategies for managing stress-related hair loss in humans.
44 citations
,
January 2008 in “Fertility and Sterility” This study suggests that androgen receptor gene CAG repeat length may influence serum free testosterone levels in some PCOS patients, with longer repeats associated with higher testosterone concentrations.
19 citations
,
February 2018 in “Nutrients” This review discusses the relationship between zinc deficiency and skin disorders, emphasizing zinc transporters' roles, but it reports no new clinical results; the authors highlight potential benefits of regulating zinc levels via transporters.
12 citations
,
January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” This case report describes a 67-year-old woman with frontal fibrosing alopecia and her daughter with lichen planopilaris, noting identical HLA D types which suggest a phenotypical link between these conditions.
11 citations
,
April 2023 in “Skin Health and Disease” This review discusses the interplay between dermatology and psychology in psychodermatology, highlighting the impact of neuroendocrine stress pathways on skin diseases and the importance of considering skin of color.