Proopiomelanocortin (POMC) and Psychodermatology

April 2023 in “ Skin Health and Disease ”

G. W. M. Millington, Hannah E. Palmer

proopiomelanocortin psychodermatology hypothalamic-pituitary-adrenal axis cutaneous corticotrophin-releasing factor corticosteroid psoriasis atopic eczema acne alopecia areata vitiligo melasma POMC HPA axis CRF steroids

Studysummary This review discusses the interplay between dermatology and psychology in psychodermatology, highlighting the impact of neuroendocrine stress pathways on skin diseases and the importance of considering skin of color.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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research Proopiomelanocortin (POMC) and Psychodermatology

11 citations , April 2023 in “Skin Health and Disease”

This review discusses the interplay between dermatology and psychology in psychodermatology, highlighting the impact of neuroendocrine stress pathways on skin diseases and the importance of considering skin of color.

research Hormonal Effects on Hair Follicles

102 citations , July 2020 in “International journal of molecular sciences”

This review discusses the effects of hormonal changes on hair follicles, concluding that hormones like androgens and estradiol significantly influence hair growth and cycle, while the roles of other hormones are still being researched.

research Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata

134 citations , July 2020 in “Experimental dermatology”

This review discusses immune privilege in anagen hair follicles and its collapse in alopecia areata, emphasizing the importance of restoring this function for effective management and disease relapse prevention.

research The Local Hypothalamic–Pituitary–Adrenal Axis in Cultured Human Dermal Papilla Cells

9 citations , June 2020 in “BMC Molecular and Cell Biology”

This study found that stress hormones, particularly CRF, can inhibit hair growth and induce hair loss by affecting human dermal papilla cells and hair follicles, suggesting a functional HPA axis in these cells.

New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

research New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

12 citations , April 2020 in “British Journal of Dermatology”

In this study, researchers found that caffeine can counteract stress-induced damage in ex vivo human androgenetic alopecia hair follicles, suggesting it may help prevent stress-related hair loss.

research Alopecia Areata: Hyperactivity of the Hypothalamic–Pituitary–Adrenal Axis Is a Myth?

5 citations , May 2017 in “Journal of the European Academy of Dermatology and Venereology”

In this study, plasma levels of MSH and cortisol in patients with alopecia areata did not show significant changes compared to healthy controls.

research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012

218 citations , April 2012 in “British Journal of Dermatology”

This updated guideline from the British Association of Dermatologists discusses current recommendations for managing alopecia areata but reports no new clinical research findings.

research Obesity and the Skin

128 citations , September 2011 in “British Journal of Dermatology”

Obesity is linked to various skin problems and may increase the risk of skin cancer.