Acne: A Potential Skin Marker of Internal Disease

    May 2015 in “ Clinics in Dermatology ”
    Joseph L. Pace
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    TLDR Acne and other skin conditions can indicate internal diseases like Polycystic Ovary Syndrome (PCOS), and early treatment can prevent long-term issues.
    Eight years ago, a study titled "Acne - a potential skin marker of internal disease" highlighted the connection between skin conditions and internal diseases, particularly Polycystic Ovary Syndrome (PCOS). The study found that Acanthosis nigricans, a skin condition characterized by velvety, thickened, hyperpigmented patches, is present in 50% of obese women and 5-10% of nonobese women with PCOS. Androgenic alopecia was also slightly more common in PCOS patients (12.5%) than in the general Western populations. The study emphasized that early diagnosis and treatment of PCOS can prevent long-term metabolic consequences and reduce emotional distress. Treatment strategies for PCOS included medication, diet, exercise, and careful management to correct insulin resistance, which in turn improves many other symptoms of the condition. Dermatologists were identified as key in recognizing and treating the syndrome early.
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