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This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.

This review suggests that the compound DRDE-07, originally a sulphur-mustard countermeasure candidate, could potentially be repurposed for skin protection due to its compatibility with pathways involved in oxidative stress and inflammation, though further experimental study is needed to confirm its therapeutic applicability in dermatology.

This study reported discovering a novel missense variant in a case of autosomal recessive woolly hair in a 31-year-old Chinese woman, which significantly reduced secretion of the encoded protein, likely leading to disease by impairing its hydrolytic function.

This study extended a skin diffusion model to include a porous pathway, effectively explaining the permeability of both polar and lipophilic solutes through the stratum corneum.

This review discusses the phytochemistry and pharmacological activities of Perilla frutescens, detailing its bioactive compounds and their potential health benefits, but reports no new clinical results.

This review discusses the potential of solid-state fermentation for extracting polyphenolic compounds from agro-industrial wastes, but it reports no new experimental results.

This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.

This study synthesized a new organic sunscreen with broad photoprotective properties and demonstrated it to be non-toxic. The resultant cream, containing nanostructured lipid carriers, showed suitable application qualities and achieved a satisfactory SPF value of 16.

This review summarizes the mechanisms by which Plumbagin, a naphthoquinone derived from plants, may impact inflammation and explores its potential biological effects, highlighting areas that require further comprehensive research before considering it for therapeutic use.

This review discusses the potential benefits of hyperthermia in cancer therapy, combined with natural compounds, to enhance treatment efficacy and reports no new clinical results.

This study reports that different Armillaria species significantly affected both the yield and active compound content of Polyporus umbellatus sclerotia, with A541 achieving the highest results.

In this study, researchers identified compound heterozygous variants in the MBTPS1 gene associated with ectodermal dysplasia features in a 14-year-old female, broadening the known disorder spectrum linked to these genetic mutations.

This study concluded that TrichoxidilTM positively affected hair growth by increasing growth factor expression and fibroblast proliferation, suggesting it may be a promising treatment for androgenetic alopecia.

This study compared auriculotherapy, Aslagh capsule, and metformin in women with PCOS, finding auriculotherapy significantly improved menstrual cycle duration and excess hair growth more than the other treatments, though all reduced these symptoms.

This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.

This study found that a combination therapy of autologous platelet-rich plasma and non-cross-linked hyaluronic acid increased hair density significantly in women with female androgenetic alopecia, without serious adverse effects.

This study found that the green alga Botryococcus terribilis and its novel compounds significantly promoted hair growth marker gene expression in hair follicle dermal papilla cells without cytotoxic effects.

In this review, the authors emphasize the importance of understanding drug chemical structures to help general physicians better manage and treat acne, although no specific results are reported.

This study successfully synthesized novel cercidin analogues from Cercidophyllum japonicum, confirming their structure via NMR data. The researchers suggest these compounds could facilitate future antibiotic development by advancing structure-activity-relationship studies.

This study found that hair cortisol concentration in free-ranging brown bears is influenced by handling methods, body condition, and potentially both short- and long-term stressors.

This review outlines recent advancements in droplet-based microfluidic technology using food-grade emulsions to create diverse delivery systems by controlling droplet size, shape, and dispersity, while also discussing challenges in scaling these processes from laboratory to industrial applications.

This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.

This study describes the PandaOmics platform, which uses AI and bioinformatics to identify new therapeutic targets and biomarkers for various diseases, demonstrating validation in laboratory and animal studies.

In this study, candidate compound 39 demonstrated potent androgen receptor antagonism and faster hair-growth efficacy in a mouse model compared to pyrilutamide, while maintaining favorable safety and pharmacokinetic profiles, suggesting potential for topical use in androgenic alopecia.

This study found that caffeic acid amide derivative, compound 4, effectively inhibited steroid 5α-reductase type 1 in vitro, suggesting potential for development as a treatment for androgenic alopecia.

This review discusses the vast potential uses of persimmon beyond its dietary benefits, including applications in sustainability and new product development, but reports no new clinical outcomes.

This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.

This study found that early biochemical screening and molecular confirmation are crucial for distinguishing profound from partial biotinidase deficiency, which supports timely treatment and management in symptomatic children.

This study reported that compound 16 (olean-12-en-3beta-ol, cinnamate) from Merremia peltata showed potential as an androgen receptor antagonist, suggesting it may benefit alopecia treatment based on molecular docking and ADME-Tox predictions.

This study investigated autophagy activator ICP5249 and found it promotes hair growth by enhancing cell proliferation and autophagy-related markers in human dermal papilla cells and hair follicles, with AMPKα playing a regulatory role, suggesting its potential as a hair growth ingredient.