2 citations
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August 2020 in “Chemical and Pharmaceutical Bulletin” This study found that rubbing increased caffeine permeation into skin primarily via hair follicles, especially when applied against the natural hair direction.
1 citations
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February 2025 This review highlights the potential health benefits of herbal-based hair oils, which incorporate ingredients like coconut oil, amla, and hibiscus, for strengthening hair, nourishing follicles, and promoting scalp health through their antibacterial and antioxidant properties.
1 citations
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January 2024 in “Journal of applied pharmaceutical science” This study investigated bacterial isolates from Xylocarpus sp. mangrove fruit and found that these symbiotic bacteria exhibit antibacterial, antifungal, and hair follicle growth properties, suggesting potential applications in the cosmetic bioindustry, particularly for treating alopecia.
1 citations
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January 2022 in “Journal of Pharmaceutical Sciences” This study developed a stable, cosmetically appealing formulation for the topical delivery of the peptide FOL-005, enhancing skin permeation and maintaining stability by keeping the peptide solid and in a water-free environment with particle sizes under 10 µm.
1 citations
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May 2019 in “International Journal of Applied Pharmaceutics” This study evaluated hair tonic and gel formulations containing Angiopteris evecta root water extract and found both fulfilled pharmaceutical preparation standards, with the 12.5% hair tonic and 10.0% gel concentrations most effective for hair growth without a significant difference in performance.
1 citations
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January 2017 in “Springer eBooks” This chapter reviews the hair follicle's role in drug and chemical penetration through the skin but does not present new experimental findings.
1 citations
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July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
April 2026 in “Research Journal of Topical and Cosmetic Sciences” In this study, researchers developed a herbal anti-dandruff shampoo using natural ingredients like Shikakai and Neem powder, aiming to effectively reduce dandruff while minimizing the side effects associated with traditional chemical-based treatments.
February 2026 in “Clinical Traditional Medicine and Pharmacology” In this study, both Unani formulations tested were effective in managing Telogen Effluvium, with Itrifal Kishneezi and Roghan Amla showing slightly faster early results in reducing hair shedding, although overall efficacy between the two treatments was comparable.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a hair serum formulated with extracts of Murraya koenigii and Clitoria ternatea demonstrated strong antifungal activity and effective dandruff management, based on laboratory evaluations.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed and evaluated a hair serum using Murraya koenigii and Clitoria ternatea extracts, finding that the F3 formulation had strong antifungal activity and was effective in dandruff management, suggesting potential benefits for scalp health.
January 2026 in “National Journal of Pharmaceutical Sciences” This study developed and validated a Gas Chromatography-Flame Ionization Detection method for assessing minoxidil, which shows good precision, accuracy, and specificity for quality control and pharmacokinetic studies.
July 2025 in “Journal of Pharmacognosy and Phytochemistry” This review explores the potential benefits of plant-based diets, herbal remedies, and phytochemicals for managing PCOS, suggesting they may help regulate menstrual cycles, improve metabolic parameters, and reduce androgen levels, offering a promising, holistic approach to treatment.
April 2025 in “Annals of Medicine” This study assessed the combination of compound glycyrrhizin and conventional treatments for alopecia areata and found it effective for promoting hair regrowth while being safe with mild adverse effects, based on a systematic review and meta-analysis of randomized controlled trials.
November 2024 in “International Journal of Social health” This study concluded that a hair-nourishing formulation combining virgin coconut oil and 4% chilli oil significantly enhanced hair growth in white rats over a 21-day period, while also exhibiting good physical stability under varying storage conditions.
June 2024 in “Pharmacon Jurnal Farmasi Indonesia” In this study, researchers evaluated different formulations of a nanoemulsion combining candlenut oil and virgin coconut oil on male rats and found that a 1:3 ratio yielded significant hair growth results, with an average hair length of 17.14 mm and a weight of 699.37 mg.
2 citations
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November 2021 in “International Journal of Applied Pharmaceutics” This study found that a phytosome lotion made from Mangkokan leaf extract, using a green solvent and microwave-assisted extraction, demonstrated greater hair growth activity than 2% minoxidil, with the 30% phytosome lotion showing the highest efficacy in increasing hair length, weight, and diameter.
2 citations
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January 2014 in “Chinese medicine” This study found that the polyherbal cough syrup Linkus reduced cough reflexes without causing observed toxicity in rats, suggesting it may be an effective and safe option.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study suggests that rice water may improve hair health by strengthening hair, reducing breakage, and promoting growth due to its nutrients and antioxidants, even as it becomes a popular ingredient in various hair care products despite limited rigorous research.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research suggests that rice water may improve hair health by reducing breakage, repairing damage, enhancing flexibility, and hydrating the scalp, making it a popular choice for natural hair care products.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit and other natural ingredients, reporting that the dye provided satisfactory color, stability, scalp pH compatibility, and did not cause irritation, also demonstrating antioxidant and antimicrobial properties that benefit scalp health.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit, finding it to be a safe, effective, and environmentally friendly alternative to synthetic dyes, with added antioxidant and antimicrobial benefits for scalp health.
20 citations
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January 2018 in “Expert opinion on emerging drugs” This review discusses the potential of Janus Kinase inhibitors for treating alopecia areata and other forms of alopecia, highlighting the need for further research on their long-term safety and optimal formulation.
October 2018 in “Annals of Reviews & Research” This open-access journal publishes innovative research articles across various fields but reports no new clinical results in this summary.
12 citations
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March 2023 in “Processes” In this study, extracts from Chenopodium quinoa, Glycine max, and Malpighia emarginata demonstrated stability, low toxicity, and effective cleaning potential as surfactants in shampoo formulations, showing performance similar to or better than commercial shampoos in terms of surface and interfacial tension and sebum removal.
July 2026 in “Antioxidants” This review identifies agri-food by-products as promising sources of antioxidant compounds for cosmeceutical applications, examining their potential for skin, oral, and hair care, while noting the need for further research on safety and clinical efficacy.
141 citations
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November 2005 in “International journal of pharmaceutics” This review examines the role of hair follicles and sebaceous glands in percutaneous drug delivery but does not report new clinical results; it calls for further exploration of follicle-targeting therapies.
79 citations
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December 2017 in “Cosmetics” This review study focused on various in vitro methods to evaluate skin permeation and retention of sunscreens, highlighting the importance of assessing sunscreen penetration due to widespread nanomaterial usage and advancements in cosmetic formulation.
60 citations
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October 2020 in “Journal of Controlled Release” This study found that curcumin nanocrystals efficiently penetrated hair follicles down to the lower infundibulum in an ex-vivo pig ear model, regardless of the gel vehicle used, though passive dermal penetration varied with the vehicle’s skin hydrating properties.
41 citations
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July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.