research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms
Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
Search
for
Sort by
Research
120-150 / 1000+ results 
research Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss
Some nutritional supplements may help treat hair loss with generally mild side effects.
research Caffeic Acid N-[3,5-Bis(Trifluoromethyl)Phenyl] Amide as a Non-Steroidal Inhibitor for Steroid 5α-Reductase Type 1 Using a Human Keratinocyte Cell-Based Assay and Molecular Dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Microneedling Combined With Compound Betamethasone in Treatment of Severe Alopecia Areata: A Case Report
Microneedling with betamethasone led to almost complete hair regrowth in severe alopecia areata.
research Promotion Effect of Constituents from the Root of Polygonum Multiflorum on Hair Growth
Compounds from Polygonum multiflorum root, especially a new one, can boost hair growth more effectively than common treatments.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Synthesis and Biological Evaluation of 4-(4-(Alkyl- and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-Steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2
The compound 4c effectively inhibits the enzyme linked to hair loss.
research Designed, Synthesis, In Vitro and Computational Analyses of Anticancer Nicotinamide Derivatives
Compound N4 effectively kills breast cancer cells and compounds N2 and N3 have strong antibacterial and antifungal properties.
research Stimulatory Effects of 6-Methylsulfinylhexyl Isothiocyanate on Cultured Human Follicle Dermal Papilla Cells
Wasabi compound may help promote hair growth.
research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
Vitexin Compound 1 may help reduce skin aging caused by UVA light.
research Effects of Taxifolin-3-O-Arabinopyranoside from Rhododendron Mucronulatum Root Extracts on the Alleviation of Hair-Loss Symptoms
The compound from Rhododendron mucronulatum roots may help treat male pattern hair loss.
research Crystal Structure and Synthesis of 17α-Acetoxy-Pregn-4,6-Diene-3,20-Dione
The compound was successfully made and shows potential for treating prostate cancer.
research Clinical Observation of Yifa Compound Treating 40 Cases of Female Pattern Hair Loss and Its Effect on Serum Dihydrotestosterone and Dehydroepiandrosterone
Yifa compound effectively treats female pattern hair loss and lowers DHT and DHEA levels.
research Nature-Derived Lignan Compound VB-1 Promotes Hair Growth by Augmenting Wnt/β-Catenin Signaling in Human Dermal Papilla Cells
VB-1, a natural compound, may promote hair growth by enhancing important cell signaling and increasing key gene expression.
research Modulating Mechanosensory Afferent Excitability by an Atypical mGluR
A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
research Synthesis, Anticancer, and Molecular Docking Studies of 2-(4-Chlorophenyl)-5-Aryl-1,3,4-Oxadiazole Analogues
The compound 4c showed strong potential as an anticancer agent.
research Efficacy Observation on Mild to Moderate Active Systemic Lupus Erythematosus Treated with Compound Zishenqing Formula
The compound zishenqing formula is effective and safe for treating mild to moderate systemic lupus erythematosus.
research Anti-Alopecic Activity of a Novel Compound from Aloe Barbadensis Miller
A compound from Aloe barbadensis Miller can help regrow hair better than minoxidil.
research Inhibition of Mitochondrial Respiration Prevents BRAF-Mutant Melanoma Brain Metastasis
Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
research Crystal Structure of 17-Beta-Benzoyloxy-16-Beta-Methylpregna-4,6-Diene-3,20-Dione
A new antiandrogen compound was made and its detailed three-dimensional shape was described.
research Experimental Assessment of 3-Meta-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-Alpha-Reductase Inhibitors in Silico and in Vivo Models
The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.
research Piperine Reduces Hair Oiliness by Inhibiting Adipogenesis of Hair Stem Cells
Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
research Crystal Structure and Synthesis of 17α-Acetoxy-6,7-Epoxypregn-4-ene-3,20-dione
A new compound was made that might help treat diseases related to male hormones.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways
Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.
research 17α-Acetoxy-6-Bromo-16β-Methylpregna-4,6-Diene-3,20-Dione: A New Steroidal Derivative with High Antiandrogenic Activity
A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
![Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions](/images/research/2aedba8c-b0ac-4fa3-9ac7-9f375a016bba/small/15581.jpg)
research Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions
Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.
research Bioengineering of Hair Follicle-Like Structure for Validation of Hair Growth Promoting Compounds
The method can test hair growth products using a lab-made hair-like structure that responds to known treatments.
research Targeted Delivery of a Poorly Water-Soluble Compound to Hair Follicles Using Polymeric Nanoparticle Suspensions
Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.
research Extractives of Cercidiphyllum Japonicum Twigs: Isolation and Structural Elucidation of a New Galloylflavonol Glycoside, Anomeric Tannins and Flavonoids
Scientists found a new natural compound and other known compounds in Cercidiphyllum japonicum twigs, which might be useful for medicine.