Anti-Alopecic Activity of a Novel Compound from Aloe Barbadensis Miller

January 2015

Anggana Ray, Pronobesh Chattopadhyay, Bolin Kumar Konwar

Aloe barbadensis Miller anti-alopecic compound chromatographic techniques cytotoxicity dermal irritancy alopecia Wistar rats warfarin topical application histological analysis hair follicle regeneration hair growth minoxidil Aloe vera hair loss hair regrowth Rogaine

TLDR A compound from Aloe barbadensis Miller can help regrow hair better than minoxidil.

The study aimed to isolate a non-toxic, non-irritant anti-alopecic compound from Aloe barbadensis Miller. Researchers used chromatographic techniques to isolate the compound and tested its cytotoxicity and dermal irritancy. Alopecia was induced in Wistar rats using warfarin, and the compound was applied topically. Histological analysis showed that the compound significantly promoted hair follicle regeneration and hair growth compared to minoxidil. The findings suggested that the isolated compound could serve as a new anti-alopecic drug, potentially replacing minoxidil.

View this study on jscimedcentral.com →

Discuss this study in the Community →

Research cited in this study

7 / 7 results

research Potentiality of Aqueous Leaf Extract of Trichosanthes Cucumerina Linn. on Hair Growth Promotion in Wistar Albino Rats

2 citations, March 2012

Trichosanthes cucumerina leaf extract can promote hair growth like Minoxidil.

Eclipta Alba Extract With Potential For Hair Growth Promoting Activity

Similar Research

5 / 426 results

research Cell-Based Model Systems for Validation of Efficacy Claims for Cosmetic Ingredients

5 citations, October 2022 in “Cosmetics”

Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.

research Skin Applications of Cannabidiol: Sources, Effects, Delivery Systems, Marketed Formulations and Safety

1 citations, March 2023 in “Phytochemistry Reviews”

CBD may improve skin and hair health, but its effective use and safety need more research.

The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance

research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance

16 citations, September 2018 in “Journal of Ethnopharmacology”

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Clionasterol-Rich Fraction of Caulerpa Racemosa Against Particulate Matter-Induced Skin Damage Via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway

research Clionasterol-Rich Fraction of Caulerpa Racemosa Against Particulate Matter-Induced Skin Damage Via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway

5 citations, September 2022 in “Antioxidants”

A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.

research Uses of Onion (Allium Cepa L.) and Aloe Vera (Aloe Barbadensis Miller) Post Hair Dye Treatment

June 2021 in “Journal of emerging technologies and innovative research”

Onion and Aloe vera can help protect hair from damage caused by hair dyes.

Anti-Alopecic Activity of a Novel Compound from Aloe Barbadensis Miller

Research cited in this study

research Potentiality of Aqueous Leaf Extract of Trichosanthes Cucumerina Linn. on Hair Growth Promotion in Wistar Albino Rats

research Eclipta Alba Extract With Potential For Hair Growth Promoting Activity

research Development and Evaluation of Polyherbal Formulation for Hair Growth-Promoting Activity

research Hair Transplanting: An Important but Often Forgotten Treatment for Female Pattern Hair Loss

research Procyanidin B-2 Extracted from Apples Promotes Hair Growth: A Laboratory Study

research Quantitative Models for the Study of Hair Growth In Vivo

research Biochemical Analysis of Hair Growth from the Aspects of Aging and Enzyme Activities

Related Community Posts Join

community Making topical finasteride solution

community What are the best hair care products for us who use minox, keto, fin, and microneedling? Share!

community Microneedling and aloe vera to recruit stem cells.

community Microneedle and aloe vera after?

community Microneedling + homemade shampoo (aloe vera mixed with rosemary water )6 months update

community Dermaroller + homemade shampoo( rosemary water+ aloe Vera+ vitamin e)