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150-180 / 1000+ resultsresearch A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients
This study identified a specific SNP in the CACNB4 gene associated with a higher risk of chemotherapy-induced alopecia in breast cancer patients, which may help develop interventions to improve their quality of life.
research Chronic Overlapping Pain Conditions and Nociplastic Pain
This study found that nociplastic type pain is a complex and heritable trait, with significant genetic overlap with multisite chronic pain and some connection to rheumatoid arthritis and a neuropathic pain phenotype.
research In vivo expression of VCAM1 precedes nephron loss following kidney tubular necrosis
In this study, researchers found that tubular VCAM1 expression in transgenic mice and human kidney transplant biopsies precedes nephron loss and fibrosis, indicating its potential as an early biomarker for tubular fate and adverse kidney outcomes.
research Inferring Spatially Resolved Transcriptomics Data from Whole Slide Images for the Assessment of Colorectal Tumor Metastasis: A Feasibility Study
In this study, deep learning models accurately predicted gene expression in whole slide images of colorectal cancer, with convolutional neural networks outperforming transformer and graph-based approaches in spatial RNA pattern prediction.
research Convolutional Neural Networks for Non-Invasive Diagnosis of Androgenetic Alopecia using Dermoscopic Hair Images
This study developed a convolutional neural network model for non-invasive diagnosis of androgenetic alopecia using dermoscopic images, demonstrating potential accuracy and scalability while highlighting the importance of model interpretability for clinical use.
research The Glucocorticoid Resistance Syndrome. Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene
In this study, researchers identified a novel genetic variant in the NR3C1 gene in a mother and her son that predicts a truncated protein, leading to glucocorticoid resistance syndrome with mild hyperandrogenic features, although no clear genotype-phenotype correlation has been established.
research Increased Circulating CXCL10 in Non-Segmental Vitiligo Concomitant with Autoimmune Thyroid Disease and Alopecia Areata
This study found that higher serum CXCL10 levels may predict the progression of non-segmental vitiligo, especially in patients also suffering from autoimmune thyroid disease and/or alopecia areata.
research Steroid Responsive Mononeuritis Multiplex in the Cronkhite–Canada Syndrome
In this case report, a patient with Cronkhite-Canada syndrome also had mononeuritis multiplex, and the authors suggest that an autoimmune mechanism may be involved based on steroid responsiveness and electrophysiological findings.
research 085 Dermal papilla cells control hair follicle matrix keratinocytes proliferation through versican
Versican in dermal papilla cells is crucial for healthy hair growth.
research Finasteride for Chronic Central Serous Chorioretinopathy
research Bio-Nanovesicle-Based Approaches for Hair and Skin Regeneration: An Updated Concise Review
This study suggests that bio-nanovesicles, such as exosomes and microvesicles, may enhance skin and hair follicle regeneration by modulating key signaling pathways, potentially overcoming the limitations of conventional treatments for alopecia and chronic skin diseases.
research Multiple cyclic nucleotide‐gated channels coordinate calcium oscillations and polar growth of root hairs
This study found that CNGC 6, CNGC 9, and CNGC 14 are crucial for maintaining calcium oscillations necessary for normal root hair growth in plants, with mutations leading to defects like swelling and bursting.
research El teorema del 0,7 o el otro teorema de Pitágoras
This report describes a Cronkhite-Canada syndrome patient with severe sepsis and disseminated intravascular coagulation successfully treated using combined therapies, including recombinant human soluble thrombomodulin.
research Presumed ocular candidiasis in drug misusers after intravenous use of oral high dose buprenorphine (Subutex)
This report notes that while surgical excision is typically curative for squamous cell carcinoma, the authors suggest considering the intralesional use of cidofovir for its potential success without systemic toxicity.
research Reflectance confocal miscroscopy and dermoscopy analysis of a case of connective tissue nevi
This study reported that connective tissue nevi show distinctive dermoscopic and RCM features, with RCM being particularly helpful for diagnosing lesions of less than one year in duration.
research Profile analysis of adverse events after boron neutron capture therapy for head and neck cancer: a sub-analysis of the JHN002 study
This study identified specific profiles and courses of adverse events associated with boron neutron capture therapy for head and neck cancer, suggesting differences based on the beam incidence site.
research Calcineurin/Nuclear Factor of Activated T-Cell Pathway in Cutaneous Squamous Cell Carcinoma
This review discusses the calcineurin/NFAT pathway's role in cutaneous squamous cell carcinoma, noting its involvement in tumor development, skin cell behavior, and the tumor microenvironment; it reports no new results.
research CuCS/Cur composite wound dressings promote neuralized skin regeneration by rebuilding the nerve cell "factory" in deep skin burns
In this study, the researchers developed a novel wound dressing incorporating copper-doped calcium silicate and curcumin, which significantly promoted nerve and blood vessel regeneration in deep burn wounds, emphasizing the crucial role of bioactive chelation in neuralized skin repair.
research BH11 Cutis verticis gyrata associated with chronic traction
In this study, two cases of cutis verticis gyrata were associated with chronic traction alopecia due to tight hairstyles, highlighting the need to consider hairstyling history in diagnosis and management.
research The Wound Healing Effect ofCallicarpa nudiflorain Scalded Rats
This study found that Callicarpa nudiflora water extract significantly accelerated wound healing and improved skin repair in deep second-degree scalds in rats, supporting its traditional medicinal use.
research B/N-doped carbon nano-onions as nanocarriers for targeted breast cancer therapy
This study reports that a new boron/nitrogen-doped carbon nano-onion-based delivery system for doxorubicin enhanced its uptake and anticancer effects in specific cancer cell types, while reducing cardiotoxicity in human heart cells.
research Connexin 26 (GJB2) mutations in keratitis–ichthyosis–deafness syndrome presenting with squamous cell carcinoma
This case report highlights the association of three CX26 gene mutations, particularly the D50N mutation, with keratitis–ichthyosis–deafness syndrome and its potential role in scalp squamous cell carcinoma and breast cancer development in a patient.
research Nanospanlastic vesicles as novel strategies for enhancing anti-glaucoma drug bioavailability
This review discusses how nanospanlastics, a type of ultra deformable vesicular nanocarrier, could enhance glaucoma management by improving the delivery and effectiveness of intraocular pressure-lowering agents, tackling adherence challenges, and advancing targeted therapies, according to the authors.
research Twenty nail onychomadesis: An unusual finding in Cronkhite–Canada syndrome
This study reports previously unreported nail features in Cronkhite-Canada syndrome, specifically recurrent onychomadesis of all 20 nails linked to systemic illness.
research Nevus lipomatosus cutaneous superficialis with folliculosebaceous cystic hamartoma
A rare skin growth was successfully removed without recurrence after one year.
research Nephronectin is Correlated with Poor Prognosis in Breast Cancer and Promotes Metastasis via its Integrin-Binding Motifs
This study suggests that nephronectin (NPNT) could serve as a novel prognostic marker for poor prognosis in a subgroup of breast cancer patients, associated with specific NPNT staining patterns.
research Exome analysis for Cronkhite-Canada syndrome: A case report
In this study, researchers found multiple somatic mutations and copy number variations in a patient with Cronkhite-Canada syndrome, providing novel insights into its potential genetic mechanisms.
research Nevus comedonicus syndrome: a case associated with multiple basal cell carcinomas and a rudimentary toe
This case report describes a 28-year-old man with widespread pigmented basal cell carcinomas and recurrent infections that were challenging to control, associated with nevus comedonicus and a rudimentary toe.
research Characteristic analysis of sebaceous nevus using dermoscopy and reflectance confocal microscopy
This study reported that imaging characteristics of sebaceous nevus vary significantly by age group, revealing dynamic developmental changes that can be effectively identified through dermoscopy and reflectance confocal microscopy, offering noninvasive diagnostic potential.