Nanospanlastic Vesicles as Novel Strategies for Enhancing Anti-Glaucoma Drug Bioavailability

January 2025 in “ The Pharma Innovation ”

Siddharth S. Kesharwani, Poonam Maurya

TLDR Nanospanlastic vesicles can improve glaucoma treatment by enhancing drug delivery to the eye.

This review discusses the potential of nanospanlastic vesicles as innovative ocular drug delivery systems for managing glaucoma, a leading cause of blindness affecting millions globally. These ultra-deformable vesicular nanocarriers offer improved corneal penetration and sustained release, enhancing the bioavailability of intraocular pressure-lowering drugs such as timolol and dorzolamide. By addressing adherence challenges and advancing targeted therapies, nanospanlastics could significantly improve treatment outcomes for glaucoma patients.

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