TLDR Nanospanlastics are effective in targeted drug delivery for chronic diseases, improving skin conditions, treating hair loss, and increasing drug absorption.
Nanospanlastics, a rapidly expanding field in nanotechnology, are being used for targeted drug delivery, particularly for the treatment of chronic human diseases. Clinical tests on psoriatic patients using SNs-selected fluidized preparation showed improvements in skin conditions, suggesting that these flexible nanovesicles have a synergistic effect on melanin formation and collagen synthesis. The study also found that sodium valproate nanospanlastics could be an effective method for treating androgenic alopecia, as they increase the permeation of celecoxib at the site of inflammation while avoiding its side effects. Additionally, the loaded epigallocatechin gallate (EGCG) spanlastics composition was found to be an efficient nanocarrier for improving EGCG bioavailability. The future of nanodrug delivery and nanomedicines appears promising due to these advancements.
19 citations,
September 2020 in “Pharmaceutics” Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.
11 citations,
January 2019 in “International Journal of Trichology” Mesotherapy is not significantly better than minoxidil for treating male hair loss.
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32 citations,
December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
32 citations,
January 2015 in “Indian Dermatology Online Journal” Minoxidil and finasteride combo maintains hair density effectively.
37 citations,
February 2014 in “Journal of Dermatology” Valproic acid increases hair count in men with hair loss.
6 citations,
April 2013 in “International Journal of Dermatology” Valproic acid helped hair growth in alopecia patient; more research needed.
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8 citations,
January 2013 in “International Journal of Trichology” The BASP classification is effective for diagnosing pattern hair loss in Indian men and women.
85 citations,
April 2012 in “PLOS ONE” Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.
19 citations,
September 2020 in “Pharmaceutics” Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.
January 2024 in “Archives of dermatological research” Both treatments for alopecia areata showed similar modest effectiveness.
[object Object] 11 citations,
January 2019 in “International Journal of Trichology” Mesotherapy is not significantly better than minoxidil for treating male hair loss.
The new gel for hair loss is safe, effective, and reduces side effects.
18 citations,
December 2015 in “PubMed” Intralesional triamcinolone is more effective than topical betamethasone for treating localized alopecia areata.
