Nevus Comedonicus Syndrome: A Case Associated With Multiple Basal Cell Carcinomas and a Rudimentary Toe

    Erkan Alpsoy, Çiçek Durusoy, Gülay Özbilim, Gülten Karpuzoğlu, Ertan Yılmaz
    TLDR A man with nevus comedonicus syndrome had multiple skin issues, including basal cell carcinomas, which improved with treatment.
    A 28-year-old man with nevus comedonicus syndrome presented with widespread black spots and cysts, recurrent infections, and a rudimentary toe. The patient developed pigmented basal cell carcinomas (BCCs) on the neck and chest, alongside comedo-like pits and erythematous papules. Histopathologic examination revealed keratin-filled follicular structures and multiple BCCs adjacent to nevus comedonicus. Treatment included amoxicillin/clavulanic acid, tretinoin gel, benzoyl peroxide, cryosurgery, and surgical removal of larger BCCs and painful cysts, resulting in some improvement. The patient remained under observation and in good health.
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