Nevus Comedonicus Syndrome: A Case Associated With Multiple Basal Cell Carcinomas and a Rudimentary Toe

    June 2005 in “ International Journal of Dermatology ”
    Erkan Alpsoy, Çiçek Durusoy, Gülay Özbilim, Gülten Karpuzoğlu, Ertan Yılmaz
    TLDR A man with nevus comedonicus syndrome had multiple skin issues, including basal cell carcinomas, which improved with treatment.
    A 28-year-old man with nevus comedonicus syndrome presented with widespread black spots and cysts, recurrent infections, and a rudimentary toe. The patient developed pigmented basal cell carcinomas (BCCs) on the neck and chest, alongside comedo-like pits and erythematous papules. Histopathologic examination revealed keratin-filled follicular structures and multiple BCCs adjacent to nevus comedonicus. Treatment included amoxicillin/clavulanic acid, tretinoin gel, benzoyl peroxide, cryosurgery, and surgical removal of larger BCCs and painful cysts, resulting in some improvement. The patient remained under observation and in good health.
    Discuss this study in the Community →

    Related Community Posts Join

    4 / 4 results

      community What are these spots on my scalp

      in Treatment  51 upvotes 1 year ago
      A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

      community Summary of future treatments from 2020

      in Chat  54 upvotes 3 months ago
      Hair loss treatments include finasteride, minoxidil, microneedling, dutasteride, CB-03-01, RU-58841, and experimental options like KY-19382 and stem cell therapy. Some treatments are considered ineffective or risky, such as ketoconazole, PRP, and low-level laser therapy.

      community New potential hair loss treatment (news release)

      in Treatment  187 upvotes 5 years ago
      New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

    Similar Research

    5 / 1000+ results
      Subject Index

      research Subject Index

      March 2014 in “Journal of The American Academy of Dermatology”
      The document lists various dermatology topics, treatments, and diagnostic methods.
      Index

      research Index

      November 2019 in “Harper's Textbook of Pediatric Dermatology”
      The document is a detailed medical reference on skin and genetic disorders.

      research Epidermal Nevi

      56 citations , October 2010 in “Pediatric Clinics of North America”
      Epidermal nevi are skin cell clusters linked to various syndromes.
      Acne Syndromes and Mosaicism

      research Acne Syndromes and Mosaicism

      1 citations , November 2021 in “Biomedicines”
      Understanding how acne develops in different diseases could lead to new treatments.