Characteristic Analysis of Sebaceous Nevus Using Dermoscopy and Reflectance Confocal Microscopy

    Qian Jiang, Hongying Chen, Ling Ma, Meng Huang, Yun Xia
    TLDR Sebaceous nevus changes with age, and dermoscopy and RCM are effective for diagnosis.
    The study analyzed the dermoscopic and reflectance confocal microscopy (RCM) characteristics of sebaceous nevus in 83 patients, categorized into four age groups. In patients under 10 years, dermoscopy revealed orange backgrounds with yellow-red cobblestone-like structures and vascular proliferation, while RCM showed underdeveloped sebaceous glands. In the 10-20 and 21-59 age groups, dermoscopy showed yellow circular structures with capillary dilation, and RCM displayed grape-like sebaceous gland structures. In patients aged 60 and above, papillomatous proliferation was the main feature. The study concluded that sebaceous nevus is a dynamically developing condition with age-specific imaging features, and both dermoscopy and RCM provided effective non-invasive diagnostic methods.
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