May 2004 in “Pediatric Dermatology” Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.
3 citations
,
May 1994 in “Journal of Pharmacology and Experimental Therapeutics” This study found that minoxidil sulfate stimulates Cl channels, potentially depolarization-activated and outwardly rectifying, in eccrine clear cells, while minoxidil itself stimulates Ca-insensitive K currents.
18 citations
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July 2006 in “British Journal of Dermatology” This study reported no Cx30 expression in normal interfollicular human epidermis and minimal expression in some skin structures, with faint detection in porokeratosis of Mibelli patient skin.
1 citations
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December 2007 in “Journal of Microbiology and Biotechnology” This study found that Minoxidil included in triamino alpha-cyclodextrin significantly promoted hair growth in mice, potentially due to its enhanced substantivity on skin.
11 citations
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April 2021 in “Advanced synthesis & catalysis” This study reports that the dye peri-xanthenoxanthene (PXX) can act as an efficient photocatalyst for various radical reactions, including complex dual catalytic processes and the synthesis of an investigational drug intermediate.
97 citations
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March 2002 in “Molecular and cellular biology” This study found that mice with a mutant CDP/Cux protein lacking the homeodomain showed severely impaired growth, high postnatal mortality, and reduced fertility, highlighting CDP/Cux's role in developmental regulation.
158 citations
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December 2002 in “Development” In this study, Msx2-deficient mice showed progressive hair loss due to shortened anagen phase and prolonged catagen and telogen phases, resulting in cyclic alopecia with structurally abnormal hair shafts.
August 2024 in “International Journal of Biological Macromolecules” This study reported that newly developed minoxidil Pickering emulsion gels, designed using cellulose stabilizers, showed promising results for promoting hair regrowth and targeting hair follicles by enhancing the delivery and stabilization properties of the formulation in a hair loss treatment context.
10 citations
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September 1997 in “Molecular carcinogenesis” This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.
January 2025 in “Biomedical Engineering Letters” This study reported that a new polymeric formulation for topical minoxidil delivery in an animal model improved hair growth and hair follicle formation more effectively than minoxidil in PBS, suggesting potential as a future hair loss treatment.
January 2025 in “Cell Communication and Signaling” This study reviews the role of the zinc finger protein CXXC5 in cellular signaling and its implications for cancer, discussing how its dysregulation is linked to various physiological and pathological processes, as well as potential therapies targeting CXXC5.
3 citations
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December 2024 in “Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512)” This study reported that meloxicam-loaded spanlastics, created using the ethanol injection method, demonstrated potential as a drug delivery system with sustained release and effective entrapment efficiency.
33 citations
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January 2009 in “Contraception” This review summarizes the use of chlormadinone acetate for hormone replacement therapy and contraception, highlighting its anti-androgenic effects, contraceptive efficacy, and clinical tolerability, without offering new clinical results.
January 2024 in “Frontiers in Bioengineering and Biotechnology” In this mouse study, researchers found that nanoparticles loaded with umbilical cord-derived stem cell membranes and minoxidil enhanced hair growth by improving drug solubility and transdermal delivery, increasing VEGF, IGF-1, MKI67, and CTNNB protein levels in skin tissue compared to regular minoxidil.
56 citations
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April 2019 in “The Plant Journal” This study found that CNGC 6, CNGC 9, and CNGC 14 are crucial for maintaining calcium oscillations necessary for normal root hair growth in plants, with mutations leading to defects like swelling and bursting.
22 citations
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April 2012 in “The American journal of pathology” This study found that the loss of Msx2 in knockout mice led to phenotypes similar to Peters anomaly and microphthalmia, suggesting that MSX2 plays a critical role in anterior segment development of the eye.
3 citations
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October 2014 in “Pharmaceutical Development and Technology” This study found that an optimized microemulsion for minoxidil with high solubility, permeation flux, and skin deposition can be achieved with specific low and high levels of certain surfactants and co-solvents.
43 citations
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September 2001 in “Annals of Neurology” This study found that somatic mosaic mutations in the doublecortin gene may cause subcortical band heterotopia in male patients, and molecular analysis using hair roots is a useful detection method.
15 citations
,
June 2021 in “International Journal of Molecular Sciences” This study demonstrated that novel curcumin analogs CMC2.24, CMC2.23, and CMC2.5 were more effective and less toxic than parent curcumin in inhibiting melanin production in normally pigmented human melanocytes, suggesting potential for skin depigmentation therapies.
March 2018 in “Chin J Reprod Contracep” This review outlines chlormadinone acetate's contraceptive and non-contraceptive applications but reports no new clinical findings, emphasizing its potential in treating dysmenorrhea and androgen-related conditions.
January 2026 in “New Journal of Chemistry” This study synthesized calcium citrate nanoparticles to improve the solubility and reduce the irritation of minoxidil solutions for treating androgenetic alopecia.
November 2016 in “The Molecular Biology Society of Japan” 1 citations
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April 2022 in “Crystal Growth & Design” 9 citations
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December 2023 in “Materials Today Bio” This study found that modified microcrystalline cellulose with citric and ascorbic acid demonstrated enhanced hemostatic properties and biocompatibility in vitro and in animal hemorrhage models.
10 citations
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January 2012 in “Journal of Oncology” This paper explores the relationship between the dermal extracellular matrix and cutaneous malignant melanoma, suggesting that ECM involvement may play a key role in the cancer's growth, invasiveness, and initial metastasis.
48 citations
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August 1998 in “Developmental Biology” In this study, researchers created a mutant mouse lacking the first cut repeat in the Cux/CDP protein, resulting in curly vibrissae and wavy hair, supporting the role of Cux/CDP's DNA binding domains in gene regulation during development.
6 citations
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February 2023 in “Genes” This study found that overexpression of the CUX1 protein promotes proliferation of Hu sheep dermal papilla cells and affects key genes in the Wnt/β-catenin signaling pathway.
28 citations
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April 2008 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” This study identified a weak interaction between minoxidil and ß-cyclodextrin in solution, forming an inclusion complex with a 1:1 molar ratio.
August 2024 in “Journal of Drug Delivery Science and Technology” In this study, the researchers reported that minoxidil-loaded transfersomes using a cyclodextrin strategy significantly increased drug stability, skin permeation, and hair regrowth in a mouse model of androgenetic alopecia compared to traditional formulations and commercial tinctures.
4 citations
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September 2011 in “American Journal of Clinical Dermatology” This case series suggests that EE/CMA 0.03mg/2mg may help manage dermatological disorders related to androgen excess, as evidenced by symptomatic improvements in the four patients treated.