Malignant Melanoma and Its Stromal Nonimmune Microecosystem
January 2012
in “
Journal of Oncology
”
cutaneous malignant melanoma stromal nonimmune microecosystem dermal extracellular matrix stromal cells Factor XIIIa CD34 versican α (IV) collagen chains neoangiogenesis metastatic spread CMM stem cells HOX gene expression sentinel lymph nodes melanoma ECM collagen angiogenesis metastasis stem cells lymph nodes
Studysummary This paper explores the relationship between the dermal extracellular matrix and cutaneous malignant melanoma, suggesting that ECM involvement may play a key role in the cancer's growth, invasiveness, and initial metastasis.
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