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In this study, a newly engineered scaffold, PADM-MX-Ag-Si@Dox, demonstrated potential as a multifunctional biomaterial for postoperative melanoma treatment by controlling drug release, enhancing wound healing, and enabling real-time tumor surveillance through temperature, pH, and electrical stimuli.

This study reported that among 10 tested 2-(4-chlorophenyl)-5-aryl-1,3,4-oxadiazole compounds, compound 4c showed the highest activity against cancer cell lines, with a 95.37% average growth rate.

In this study, researchers developed a 3D in-vitro system for generating functional AT-resident macrophages without cell sorting, providing a valuable tool to study their differentiation and function in various physiological and pathological conditions.

The I National Academic Congress of Dermatology in 2021 expanded to include participants from across Brazil and discussed dermatology topics, including COVID-19.

This study suggests that hair cortisol measurement could serve as an alternative diagnostic method for Cushing’s disease, showing acceptable concordance with urinary free cortisol despite differing evaluated periods.

This case study reports a rare instance of an estradiol-secreting adrenocortical carcinoma in a 58-year-old male, causing feminization and Marie-Antoinette syndrome, with potential paraneoplastic aortitis.

This case study of a 2-month-old boy with maple syrup urine disease highlights the dangers of restricting branched-chain amino acid intake, as it led to acrodermatitis dysmetabolica-like skin eruptions and hair loss, later resolved with careful dietary adjustments and monitoring.

This study presents an improved reference genome for the African spiny mouse, which may aid in understanding its tissue regeneration at the molecular level.

This study supports the use of the chicken chorioallantoic membrane as an effective pre-clinical model for burn wound research and the screening of new therapeutic agents.

This study used in vivo confocal microscopy and a ResNet34 deep learning model to classify meibomian gland images with an AUROC greater than 0.95, indicating its potential for automatic diagnosis and screening of meibomian gland dysfunction.

The Celsr1 gene is crucial for normal hair patterning in mice.

In this study, minoxidil nanoparticles significantly increased hair growth rate in C57BL/6 mice compared to traditional minoxidil, suggesting enhanced effectiveness and potential as a new formulation.

This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.

In this study, researchers developed a method to create skin organoids using spinning bioreactors, facilitating efficient high-throughput drug screening, and found that Minoxidil activates the Wnt/beta-catenin signaling pathway in these models.

In this study, researchers generated a mouse mutation called scraggly, related to hair and skin defects, and mapped it to a genetic location on mouse Chromosome 19 distinct from similar mutations.

Researchers created a new mouse model for studying scleroderma.

This study demonstrates that melanocyte stem cells can be a source of melanoma in a mouse model, resembling human melanoma in both heterogeneity and gene signatures.

This study found that factors released by mesenchymal stromal cells can enhance the proliferation and migration of keratinocytes in vitro, which may contribute to improved understanding of their role in wound healing and potential applications in dermal regeneration therapies.

This case report describes a 6 1/2-year-old girl with significant height growth and early pubic hair development.

Ethinylestradiol/Chlormadinone Acetate is a safe and effective birth control pill that also helps regulate menstrual cycles, reduces period pain, and treats certain skin and hair conditions.

This study used an in silico/in vitro approach to identify potential inhibitors of the enzyme SRD5A2, finding that the androgen receptor modulator MK-0773 is a moderate inhibitor, although it does not act as a covalent inhibitor like finasteride.

In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.

This study established a murine chronic graft-versus-host disease model with scleroderma features, showing typical skin changes and cellular infiltrates associated with the condition.

Martin-Perez et al. show that rapamycin's beneficial effects in a mouse model of Leigh syndrome are linked to the downregulation of protein kinase C.

Two studies in Cell Stem Cell reported that human and mouse somatic cells can be reprogrammed into induced pluripotent stem cells using microRNAs, eliminating the need for ectopic protein expression.

This study interpreted McDonald's Father's Day advertising posters using semiotic analysis, finding that the imagery and text symbolically represent a father figure and McDonald's branding to celebrate the occasion.

This research highlights the potential of non-coding RNAs as biomarkers and therapeutic targets in dermatology, while experimental studies on a unique GVM case suggest CCM2L may modulate disease severity, advancing understanding of genetic mechanisms in rare skin disorders.

This study suggests that estimating autism likelihood as early as one month after birth may enable more precise early intervention for children with developmental support needs, potentially improving diagnosis, workflows, and reducing service wait times.

This study introduced a new adaptive microrhizotron for non-destructive observation of pepper root traits, finding that specific installation patterns significantly enhanced root interception probability while effectively measuring root architecture for plant research.