Ethinylestradiol/Chlormadinone Acetate: Benefits and Efficacy
January 2004
in “
Drugs
”
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Studysummary Ethinylestradiol/Chlormadinone Acetate is a safe and effective birth control pill that also helps regulate menstrual cycles, reduces period pain, and treats certain skin and hair conditions.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document from 19 years ago, written by Hans Peter Zahradnik, discussed the benefits of the oral contraceptive Ethinylestradiol/chlormadinone acetate (EE/CMA). The contraceptive was found to be very effective, with adjusted Pearl indices between 0.04 and 0.076. It had positive effects on menstrual cycle regulation and abnormal bleeding, and was well-tolerated, leading to excellent compliance in phase III and postmarketing surveillance studies. Notably, it significantly reduced dysmenorrhoea. The antiandrogenic effect of EE/CMA was confirmed, leading to clinical efficacy in mild-to-moderate androgen-induced skin and hair disorders, including androgenic alopecia. The rate of venous thromboembolism was very low. The study concluded that EE/CMA was an effective and safe method of contraception with clear additional benefits.