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GlossaryChlormadinone Acetate (CMA)

synthetic hormone used in contraceptives and hormone therapy

Chlormadinone Acetate (CMA) is a synthetic progestin, a type of hormone similar to the natural hormone progesterone. It is commonly used in hormonal contraceptives and hormone replacement therapy to regulate menstrual cycles, treat endometriosis, and manage symptoms of menopause. Additionally, it has anti-androgenic properties, which means it can help reduce the effects of male hormones, making it useful in treating conditions like acne and hirsutism (excessive hair growth).

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research Efficacy of an Oral Contraceptive Containing EE 0.03 mg and CMA 2 mg (Belara) in Moderate Acne Resolution: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial

42 citations , May 2009 in “Contraception”

The oral contraceptive with ethinyl estradiol and chlormadinone acetate is effective in treating moderate acne.

research Acne Resolution Rates: Results of a Single-Blind, Randomized, Controlled, Parallel Phase III Trial with EE/CMA (Belara®) and EE/LNG (Microgynon®)

88 citations , January 2001 in “Dermatology”

EE/CMA is more effective than EE/LNG in reducing acne.

research Preparation and Characterization of Soluble Wool Keratin for Human Hair Care

January 2013 in “Transactions of the Materials Research Society of Japan”

CMADK reduces hair damage from bleaching and permanent waving.

research Profile of the Progesterone Derivative Chlormadinone Acetate: Pharmacodynamic Properties and Therapeutic Applications

33 citations , January 2009 in “Contraception”

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

research Identification of Novel Hair-Growth Inducers by Means of Connectivity Mapping

30 citations , December 2009 in “The FASEB Journal”

Fluphenazine and iloprost can induce hair growth.

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community Has anyone used the new liposomal topical fin from Hasson and Wong?

6 upvotes 9 years ago

The conversation discusses a new liposomal topical finasteride from Hasson and Wong, available in Canada and Italy, soon in the US, costing $40/month. It claims to reduce scalp DHT by 50% without affecting serum DHT, potentially benefiting those who can't tolerate oral finasteride or RU58841.

community Pp405 phase 2a clinical results

in Research/Science 39 upvotes 5 months ago

PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

community MY 6 MONTH TRANSFORMATION PROGRESS

in Progress Pictures 210 upvotes 1 year ago

A 23-year-old male shared his 6-month hair transformation using Dutasteride, oral Minoxidil, ketoconazole shampoo, vitamin D, gym, cardio, and dermastamping. He reported significant hair maintenance and no side effects.

community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

in Minoxidil 33 upvotes 1 year ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.