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GlossaryChlormadinone Acetate

synthetic hormone used in contraceptives and hormone therapy

Chlormadinone Acetate (CMA) is a synthetic progestin, a type of hormone similar to the natural hormone progesterone. It is commonly used in hormonal contraceptives and hormone replacement therapy to regulate menstrual cycles, treat endometriosis, and manage symptoms of menopause. Additionally, it has anti-androgenic properties, which means it can help reduce the effects of male hormones, making it useful in treating conditions like acne and hirsutism (excessive hair growth).

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research Foreword

September 2011 in “American Journal of Clinical Dermatology”

The birth control pill containing ethinylestradiol and chlormadinone may help treat acne and other skin and hair conditions related to hormones.

research Effects of Two Estroprogestins Containing Ethinylestradiol 30 μg and Drospirenone 3 mg and Ethinylestradiol 30 μg and Chlormadinone 2 mg on Skin and Hormonal Hyperandrogenic Manifestations

31 citations, January 2008 in “Gynecological endocrinology”

Both birth control pills improved hormone levels and skin conditions in women with hyperandrogenism, but the one with drospirenone was more effective.

Effects of an Oral Contraceptive Containing Chlormadinone Acetate and Ethinylestradiol on Hair and Skin Quality in Women Wishing to Use Hormonal Contraception

research Effects of an Oral Contraceptive Containing Chlormadinone Acetate and Ethinylestradiol on Hair and Skin Quality in Women Wishing to Use Hormonal Contraception

6 citations, March 2012 in “Journal of the European Academy of Dermatology and Venereology”

The oral contraceptive improved hair and skin quality in women.

research Efficacy of an Oral Contraceptive Containing EE 0.03 mg and CMA 2 mg (Belara) in Moderate Acne Resolution: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial

42 citations, May 2009 in “Contraception”

The oral contraceptive with ethinyl estradiol and chlormadinone acetate is effective in treating moderate acne.

research Symposium on Women's Dissatisfaction with Traditional Contraceptive Methods and Alternatives

January 2008 in “The European Journal of Contraception & Reproductive Health Care”

Non-daily contraceptives cause fewer side effects and are more satisfying to women, and certain oral contraceptives can treat acne and seborrhoea, with a combination of chlormadinone acetate and ethinyl estradiol being highly effective and safe.

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