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Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.

Minoxidil boosts hair growth by increasing cell production and survival.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The PIP5K1A gene helps cashmere growth in goats by promoting cell proliferation, and melatonin boosts its expression.

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Procyanidin B-2 from apple juice significantly increases hair growth and may be more effective than minoxidil without side effects.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.

The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.

Policosanol helps treat hair loss by balancing hormones and supporting hair growth.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

The document concludes that a new biosensor can efficiently detect prostate cancer cells and that standardized referrals help find significant cancers effectively.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Apoptosis is essential for human skin development and forming a functional epidermis.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.