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540-570 / 1000+ resultsresearch PROCEEDINGS OF THE INTERNATIONAL RESEARCH, EDUCATION & TRAINING CENTER
research The regenerative wound healing effects and molecular mechanism of Isaria cicadae Miquel rice fermentation extract
This study suggests that Isaria cicadae Miquel rice fermentation extract may enhance regenerative wound healing of hair follicles in mouse skin through the Hippo pathway mechanism.
research Presentación en el CITA de los resultados del proyecto “Estudio Integral del Cabrito Lechal Español”
This analysis examines how faculty-related Instagram accounts have adapted their posts during the recent application cycle, including showcasing credentials and incorporating new virtual engagement tools, but reports no new research findings.
research ISID1116 – Novel androgen receptor degrader for androgenetic alopecia (AGA) application
In this study, a newly designed protein degrader targeting androgen receptors showed promise in reversing hair regrowth inhibition in a mouse model of androgenetic alopecia, suggesting potential as a novel and safe treatment strategy.
research Cepharanthine Dry Powder Inhaler for the Treatment of Acute Lung Injury
In this study, dry powder inhalers containing Cepharanthine were administered to rats with acute lung injury, significantly reducing pulmonary edema, hemorrhage, and inflammatory markers, suggesting its potential as an effective anti-inflammatory treatment when inhaled directly into the lungs.
research Revisión sistemática de los efectos adversos cutáneos causados por fármacos inhibidores de los puntos de control inmunitario: características, manejo y pronóstico
This review discusses the characteristics and treatment recommendations for skin-related adverse effects from immune checkpoint inhibitors in cancer treatment, and notes an observed association with favorable oncology outcomes that requires careful interpretation.
research Cepharanthine induces the proliferation of human dermal papilla cells and stimulates vascular endothelial growth factor expression through increased intracellular calcium mobilization and hypoxia‐inducible factor activation
This study found that cepharanthine and its structural analogues may stimulate hair growth by promoting the proliferation of human dermal papilla cells and increasing VEGF expression in vitro.
research Información gratuita Trasplante de Cabello Fue
research Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice
This study found that mature dermal adipocytes have high plasticity, undergoing dedifferentiation and redifferentiation, which plays a significant role in hair cycling and wound healing.
research Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury
This study reports that sebaceous glands can regenerate after injury through stem cell plasticity, with hair-follicle-derived stem cells replacing sebaceous gland progenitors and playing a crucial role in the regeneration process, which is dependent on FGFR2 signaling and aided by hair growth induction.
research Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors
This study demonstrated that cultured epidermal stem cells and skin-derived precursors can regenerate functional hair follicles and sebaceous glands in both mice and adult humans, suggesting potential for bioengineered skin substitutes.
research Genetically modified laboratory mice with sebaceous glands abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research Single‐cell transcriptomics reveals a senescence‐associated IL ‐6/ CCR6 axis driving radiodermatitis
This study found that targeting IL-6, IL-1, and CCR6 signaling pathways may effectively reduce irradiation-induced alopecia and dermatitis in radiotherapy patients.
research Mechanistic and therapeutic insight into the effects of cinnamon in polycystic ovary syndrome: a systematic review
This review indicates promising potential for cinnamon supplementation to improve metabolic outcomes in PCOS, but more clinical trials with higher doses and longer durations are needed to confirm these effects.
research Potential Role of Cinnamon (Cinnamomum verum) to Reduce the Risk of Polycystic Ovary Syndrome by Managing the Obesity: A Review
This review investigates the potential benefits of cinnamon supplementation alongside lifestyle changes for managing obesity and polycystic ovary syndrome, but it reports no new clinical results.
research Comparative histomorphometric and transcriptomic analysis reveals potential genetic determinants of pelage variation between hairy and coarse-woolly sheep
This study identified genetic differences between Australian White Sheep and Hu Sheep that may explain their distinct pelage types, with a focus on subcutaneous adiposity and immunoregulation. The findings suggest potential targets for breeding climate-resilient sheep, enhancing our understanding of heat tolerance in these breeds.
research Screening of Protein Related to Wool Development and Fineness in Gansu Alpine Fine-Wool Sheep
In this study, researchers using Astral—DIA proteomics technology identified 67 differentially expressed proteins in Gansu alpine fine-wool sheep, linking proteins like keratin and MGST3 in pathways to wool fineness regulation, particularly highlighting their association with hair follicle development.
research Brown adipose tissue in the form of innovative approach for polycystic ovary syndrome treatmentstill long time to reach clinical arena: a narrative review
This review discusses the potential role of brown adipose tissue in managing polycystic ovary syndrome and reports no new clinical results; it highlights a need for further research on this therapeutic avenue.
research Dwarf planet Ceres and the ingredients of life
The Dawn spacecraft found that Ceres has complex organic molecules and a lot of water ice, hinting it might support life.
research A Cluster of (Old) Portuguese Derivational Suffixes:-ece, -ice, -ez(a),Viewed in Relation to their Spanish Counterparts
This article reviews the history of Portuguese and Spanish derivational suffixes and provides no new empirical findings, discussing various scholarly works and contributions on the subject.
research Icariside II inhibits gastric cancer progression by suppressing the Wnt/β-catenin signaling pathway
This study observed that Icariside II, an extract from Epimedium brevicornu Maxim, can inhibit the growth of gastric cancer in cell lines and mouse models by promoting apoptosis and suppressing the Wnt/β-catenin signaling pathway, with minimal toxicity to normal gastric cells.
research Cutaneous Lesions in the Rat Following Administration of an Irreversible Inhibitor of erbB Receptors, Including the Epidermal Growth Factor Receptor
This study found that CI-1033 caused skin lesions in rats that resemble effects seen in humans receiving EGF receptor inhibitors, suggesting this animal model can help explore the mechanisms behind this cutaneous toxicity.
research Ishige sinicola extract stimulates osteoblast proliferation and differentiation via the bone morphogenetic protein 2/runt-related gene 2 signalling pathway
This study found that Ishige sinicola extract stimulated osteoblast differentiation and bone formation in MC3T3-E1 cells, suggesting potential use for osteoporosis prevention and treatment.
research p53‐dependent transcriptional regulation of EDA2R and its involvement in chemotherapy‐induced hair loss
In this study, researchers reported that the activation of EDA2R by p53 leads to p53-dependent cell death in cancer cells and is involved in chemotherapy-induced hair loss.
research A 56-Day Randomized, Double-Blinded, and Placebo-Controlled Clinical Assessment of Scalp Health and Hair Growth Parameters with a Centella asiatica Extracellular Vesicle and Growth Factor-Based Essence
This study found that applying a topical scalp essence with Centella asiatica extracellular vesicles and growth factors significantly improved scalp health and hair growth compared to a placebo after 56 days.
research High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
In this study, the researchers identified CEP135 as a biomarker linked to poor sarcoma survival and suggested PLK1 as a potential therapeutic target for sarcoma patients with high CEP135 expression.
research Centella asiatica L. Urb. Extracellular Vesicle and Growth Factor Essence for Hair and Scalp Health: A 56-Day Exploratory Randomized Trial
In this exploratory randomized controlled trial, participants using a combination of Centella asiatica-derived extracellular vesicles with recombinant growth factors showed significant improvements in hair thickness, density, length, and reduced hair loss and scalp sebum content after 56 days, compared to placebo.
research PandaOmics: An AI-Driven Platform for Therapeutic Target and Biomarker Discovery
This study describes the PandaOmics platform, which uses AI and bioinformatics to identify new therapeutic targets and biomarkers for various diseases, demonstrating validation in laboratory and animal studies.
research Secondary Syphilis in Cali, Colombia: New Concepts in Disease Pathogenesis
This study provides quantitative evidence that secondary syphilis is highly endemic in Cali, Colombia, and many untreated patients have high numbers of circulating Treponema pallidum spirochetes.