7 citations
,
June 2015 in “The anatomical record” This study in Hexi cashmere goats found that secondary follicle activity increases with time, and Hoxc13 expression varies significantly across different growth stages, suggesting a role in follicle activity.
9 citations
,
January 2015 in “Medical hypotheses” This report suggests that TCDD may alter human epidermal stem cell populations by upregulating c-Myc, potentially leading to increased stem cell turnover during chloracne development.
January 2017 in “Dermatology Review” This article discusses skin lesions in chronic graft-versus-host disease and highlights the importance of coordinated care between haematologists and dermatologists for effective management; it presents no new clinical results.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that in a mouse model of Focal Dermal Hypoplasia, treatment with lithium carbonate improved skin disease symptoms compared to controls, though disease severity varied and posed interpretation challenges.
23 citations
,
August 1983 in “PubMed” This case report details a 17-year-old girl with systemic lupus erythematosus and recurrent infections linked to a complete isolated Clq deficiency.
15 citations
,
January 2013 in “European Journal of Pediatrics” Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.
March 2022 in “Indian Journal of Animal Research” In this study, canine hair follicle stem cells were shown to be multipotent, capable of differentiating into various cell types like adipocytes in vitro.
February 2026 in “Biophysical Journal”
81 citations
,
June 2012 in “European journal of human genetics” This review outlines a diagnostic framework for clinicians to distinguish different types of inherited ichthyoses and suggests further testing and treatment strategies, but reports no new clinical results.
111 citations
,
May 2001 in “Human reproduction update” This review discusses the role of genetic mutations and environmental endocrine disruptors in insufficient androgen action, which can result in conditions like hypospadias, cryptorchidism, and micropenis, during male fetal development.
17 citations
,
October 2001 in “Veterinary dermatology” This case report indicates that epidermal dysplasia in two West Highland White Terriers might be caused by a reaction to Malassezia infection or self-trauma, rather than being congenital.
14 citations
,
October 2022 in “Journal of the American Heart Association” This study found that among older men, lower calculated free testosterone was significantly associated with a higher risk of heart failure, suggesting a possible role of testosterone deficiency in heart failure incidence.
10 citations
,
July 2015 in “Veterinary Dermatology” This study found that noninflammatory alopecia in dogs can be caused by exposure to estradiol gel used by their owners for postmenopausal symptoms, with hair regrowth observed after minimizing exposure.
9 citations
,
January 2015 in “Veterinary record case reports” This study reports the first successful treatment of a dog infected with Mycobacterium avium subspecies hominissuis using antibiotics, with no zoonotic transmission observed.
3 citations
,
January 2021 in “Veterinary dermatology” This study describes a rare form of congenital alopecia in domestic short hair cats, characterized by hair shaft defects and follicular dystrophy similar to those seen in certain mutant mouse strains.
October 2025 in “Indian Dermatology Online Journal” In this study, researchers found that a 2.5 mg/mL concentration of triamcinolone acetonide was more effective than a 1.25 mg/mL concentration for promoting hair regrowth in patients with limited patchy alopecia areata, with significant differences in regrowth observed after six months.
May 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found potential evidence of inducible skin-associated lymphoid tissue (iSALT) in alopecia areata patients undergoing topical immunotherapy, which may suggest an essential role in treatment efficacy.
September 2024 in “The Journal of Dermatology” In this study, researchers reported a rare case of nevus comedonicus with hair growth in a 26-year-old male, challenging prior reports that affected lesions typically lack the capability to develop terminal hair.
July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” This article reviews the potential causes of insufficient androgen action during fetal development, such as enzyme and receptor gene mutations or environmental disruptors, but reports no new results.
March 2022 in “Journal of Cosmetic Dermatology”
4 citations
,
January 1992 in “The Tohoku Journal of Experimental Medicine” In this study, chronic zinc chloride administration in mice led to the replacement of long coarse hairs with short fine hairs, while overall skin histology remained normal.
December 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study revealed that Patched receptors establish a Hedgehog signaling gradient in developing hair follicles, which may influence their formation and potentially offer a diagnostic tool for distinguishing Hedgehog-driven tumors.
November 2011 in “Molecular Cancer Therapeutics” This study discusses the involvement of Hedgehog signaling in various human cancers, detailing different mechanisms of pathway activation and highlighting the potential for therapeutic targeting through pathway inhibition.
2 citations
,
May 1985 in “Environmental Health Perspectives” This report examines the mechanisms by which TCDD affects human epidermal and carcinoma cells, aiming to create a risk assessment model for halogenated aromatic compounds, but presents no new clinical results.
April 2023 in “Journal of Investigative Dermatology” In this study, researchers developed a mouse model of scarring alopecia and observed significant reductions in CD200R expression in affected skin, potentially linking this signaling pathway to immune attacks on hair follicles and suggesting new treatment targets for scarring hair loss.
1 citations
,
July 2017 in “PubMed” This study describes two Danish cases of Cronkhite-Canada syndrome presenting with malnutrition and gastrointestinal issues; both patients underwent successful treatment and remission after developing colonic adenocarcinomas.
24 citations
,
January 2019 in “Theranostics” This study found that loss of the Pten gene in Lgr5+ hair follicle stem cells promoted squamous cell carcinoma formation through the Akt/β-catenin signaling pathway.
21 citations
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October 1980 in “Gastroenterology” This report is the first to associate Cronkhite-Canada syndrome with multiple myeloma, describing regenerative pseudopolyps in a 58-year-old woman rather than true adenomatous polyps.
11 citations
,
January 2016 in “The Journal of Sexual Medicine” This study found that young women with nonclassic congenital adrenal hyperplasia had impaired sexual function and mild depressive symptoms compared to healthy women.
1 citations
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November 2022 in “Journal of the Endocrine Society” This study found that US adults with classic congenital adrenal hyperplasia most preferred a hypothetical adjunctive therapy that prevents glucocorticoid-induced weight gain over other potential benefits.