Circulating Androgen Concentrations and Risk of Incident Heart Failure in Older Men: The Cardiovascular Health Study

    October 2022 in “ Journal of the American Heart Association ”
    Joyce Njoroge, William Tressel, Mary L. Biggs … Jorge R. Kizer
    Studysummary This study found that among older men, lower calculated free testosterone was significantly associated with a higher risk of heart failure, suggesting a possible role of testosterone deficiency in heart failure incidence.
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    Research cited in this study 5

    1. Serum Androgens and Risk of Atrial Fibrillation in Older Men: The Cardiovascular Health Study Clinical cardiology · 2018
    2. Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction Circulation · 2015
    3. Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2014
    4. Clinical Biochemistry of Dihydrotestosterone Annals of Clinical Biochemistry · 2013
    5. Exogenous Testosterone Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum Testosterone The Journal of Clinical Endocrinology and Metabolism · 2005