Selective Complete C1q Deficiency Associated With Systemic Lupus Erythematosus
August 1983
in “
PubMed
”
TLDR Clq deficiency is linked to systemic lupus erythematosus symptoms.
The document reported a case of a 17-year-old girl from Saudi Arabia with systemic lupus erythematosus (SLE) and recurrent infections linked to a selective complete deficiency of Clq. Despite fulfilling the ARA criteria for SLE, she did not have antibodies to DNA or low levels of C3 or C4, but her total serum hemolytic complement activity was absent due to the complete absence of Clq. The study reviewed existing literature on isolated selective complete Clq deficiency associated with clinical disease.
