Two Cases of the Rare Cronkhite-Canada Syndrome
July 2017
in “
PubMed
”
New to Prednisolone? There is a guide in the encyclopedia. Read the guide → Studysummary This study describes two Danish cases of Cronkhite-Canada syndrome presenting with malnutrition and gastrointestinal issues; both patients underwent successful treatment and remission after developing colonic adenocarcinomas.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Cronkhite-Canada syndrome (CCS) was a rare, non-heritable condition characterized by gastrointestinal polyposis, dysgeusia, malnutrition, total alopecia, and onychodystrophia. This report detailed two Danish cases: an 88-year-old female and a 69-year-old male, both presenting with malnutrition, dyspepsia, vomiting, dysgeusia, and hair loss. Upper endoscopy revealed marked edema and polyposis in the stomach. Both patients developed colonic adenocarcinomas, which were surgically removed. Treatment included hyperalimentation, prednisolone, and azathioprine, leading to remission in both patients, with the first patient achieving total remission.
