TLDR Two patients with Cronkhite-Canada syndrome achieved remission after treatment.
Cronkhite-Canada syndrome (CCS) was a rare, non-heritable condition characterized by gastrointestinal polyposis, dysgeusia, malnutrition, total alopecia, and onychodystrophia. This report detailed two Danish cases: an 88-year-old female and a 69-year-old male, both presenting with malnutrition, dyspepsia, vomiting, dysgeusia, and hair loss. Upper endoscopy revealed marked edema and polyposis in the stomach. Both patients developed colonic adenocarcinomas, which were surgically removed. Treatment included hyperalimentation, prednisolone, and azathioprine, leading to remission in both patients, with the first patient achieving total remission.
1 citations,
June 2015 in “Australasian Journal of Dermatology” A patient with Cronkhite-Canada syndrome improved with nutritional support and steroids, but early diagnosis is key due to high mortality.
16 citations,
May 2013 in “Australasian Journal of Dermatology” Hair loss in Cronkhite-Canada syndrome is reversible by treating the gut issues and doesn't need steroid treatment for the hair itself.
19 citations,
May 1984 in “Digestive diseases and sciences” A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
5 citations,
March 2013 in “International journal of surgical pathology” Cronkhite-Canada syndrome can be diagnosed without gastrointestinal polyps if there is severe mucosal atrophy and edema.
October 2019 in “Journal of Evolution of Medical and Dental Sciences” A 56-year-old man was diagnosed with Cronkhite-Canada Syndrome after showing symptoms like diarrhea, weight loss, and skin changes.
