Case of Cronkhite-Canada Syndrome - A Non-Inherited Gastrointestinal Polyposis Syndrome

    October 2019 in “ Journal of Evolution of Medical and Dental Sciences ”
    Arun Solanki, Rajesh Bhurkunde
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    TLDR A 56-year-old man was diagnosed with Cronkhite-Canada Syndrome after showing symptoms like diarrhea, weight loss, and skin changes.
    A 56-year-old male with Cronkhite-Canada Syndrome presented with non-bloody watery diarrhea, weight loss, and hyperpigmentation over the face and extremities. He experienced frequent loose stools, sometimes mixed with blood, but without mucosa or fat, and unrelated to food, stress, or drugs. Physical examination revealed hyperpigmentation, alopecia, and dystrophic nail changes, but no oral pigmentation or signs of vitamin deficiency. Laboratory tests showed hypocalcemia and hypoalbuminemia, while other parameters were normal. Colonoscopy revealed multiple polypoidal lesions from the distal transverse colon to the rectum, confirming the diagnosis.
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